Bus Tickets from Chicago to Louisville

Next departures

Next departures for Chicago to Louisville on October 14
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc.
Downtown Greyhound Station
Louisville, KYCheapest
FlixBus
Chicago 95Th & Dan Ryan
Louisville, KYFastest
Amtrak
Chicago (Union Station), IL
Louisville, KYNo tags
Greyhound Lines, Inc.
Downtown Greyhound Station
Louisville, KYNo tags
FlixBus
Downtown Greyhound Station
Louisville, KYNo tags

Last refresh of the prices: Today at 12:17 AM CDT.

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Bus Chicago to Louisville: Trip Overview

Average Ticket PriceUS$53
Average Bus Trip Duration6h 45m
Number of daily buses17
Earliest bus departure12:30am
Distance417 km
Latest bus departure11:59pm

Chicago to Louisville Bus

With Busbud, comparing and booking tickets for a bus from Chicago to Louisville is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from Chicago to Louisville from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses travelling from Chicago to Louisville, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Chicago - Louisville

  1. What is the distance between Chicago and Louisville?

    The distance covered from Chicago to Louisville is 432 km (268 miles).

  2. What are the departure and arrival locations for buses traveling from Chicago to Louisville?

    Buses traveling this route start their trip at Downtown Greyhound Station, in Chicago, and end it at Louisville Greyhound Bus Station, in Louisville.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
10-11
US$50
10-12
US$142
Today
US$50
10-14
US$42
10-15
US$40
10-16
US$28
10-17
US$31
10-18
US$28
busbud logoThe cheapest trip from Chicago to Louisville was searched and found on Oct 16, 2025 with a price of US$28

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to Louisville, as early as possible.

You can expect to pay from US$28 to US$142 for a bus ticket from Chicago to Louisville based on the last 2 days. You can expect to find the cheapest price for the trip at US$28 which is on 2025-10-16.

Usually Amtrak will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Chicago to Louisville.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Chicago to Louisville, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Chicago to Louisville that are otherwise impossible to come by with a plane.

Tune out to the fine sounds of your best music playlist on your bus trip from Chicago to Louisville while indulging in miles on end of beautiful scenic views.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Will you be returning to Chicago by bus?

Bus from Louisville to Chicago

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

People from around the world trust Busbud

‌

Popular Buses Connecting Chicago

Buses Leaving from Chicago

Buses Going to Chicago

Popular Buses Connecting Louisville

Buses Leaving from Louisville

Buses Going to Louisville