Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Downtown Greyhound Station | Mesa Bus Stop | Cheapest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Chicago 95Th & Dan Ryan | Mesa Bus Stop | Fastest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Downtown Greyhound Station | Mesa Bus Stop | No tags | ||||
| Bus | 537-517 W. Jackson Blvd | Mesa Bus Stop | No tags | ||||
| Bus | 537-517 W. Jackson Blvd | Mesa Bus Stop | No tags |
Last refresh of the prices: Last Saturday at 12:11 AM CST.
Get from Chicago to Mesa
The journey takes about 1 day, 21 hours 40 minutes, and with fares starting at just R 3 874, it presents an excellent value for a comfortable ride.
Where are the popular stops in Chicago and Mesa?
Stops in Chicago
- A630 W Harrison St, Chicago, IL 60607, USA
- B
Chicago O'Hare International Airport
- C
Polk St & Canal St
500-536 W Polk St, Chicago IL 60607, USA - D
Tornado Bus S Kedzie Ave
2807 S Kedzie Ave, Chicago, IL 60623, USA - E
Cumberland CTA
5800 N Cumberland Ave, Chicago, IL 60631, USA - F
Turimex California Ave
2139 S California Ave, Chicago, IL 60608, USA
Stops in Mesa
- A
Mesa Bus Station
1423 S Country Club , Mesa, AZ 85210, USA
Compare bus companies
Frequently asked questions about travelling from Chicago to Mesa by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Chicago to Mesa?
The cheapest bus tickets from Chicago to Mesa start at R 3 874. The average price for this route is around R 5 737. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Chicago to Mesa?
The average bus journey time from Chicago to Mesa is 1d 21h, covering a distance of 2321 km. The fastest bus gets you there in 1d 18h and is operated by Greyhound.
Which bus companies service the Chicago to Mesa route?
What is the earliest and latest departure time for the bus from Chicago to Mesa?
The earliest bus departs from Chicago to Mesa at 10:00. And the latest bus departs at 23:10.
What are the CO₂ emissions for the bus trip from Chicago to Mesa?
A bus trip from Chicago to Mesa produces an estimated 58 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
What is the best bus company from Chicago to Mesa?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87435 reviews.
Which bus company has the best Wi-Fi from Chicago to Mesa?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company offers the most punctual service from Chicago to Mesa?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Chicago to Mesa?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Chicago to Mesa was searched and found on 31 Dec 2025 with a price of R 4 143To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to Mesa as early as possible.
You can expect to pay from R 4 143 to R 7 300 for a bus ticket from Chicago to Mesa based on the last 2 days. You can expect to find the cheapest price for the trip at R 4 143, which is on 2025-12-31.
