Bus Tickets from Chicago to Mesa

Next bus departures

Next departures for Chicago to Mesa on November 22
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus + Greyhound Lines, Inc.
Bus
Chicago 95Th & Dan Ryan
Mesa Bus StopCheapest
FlixBus + Greyhound Lines, Inc.
Bus
Chicago 95Th & Dan Ryan
Mesa Bus StopFastest
FlixBus + Greyhound Lines, Inc.
Bus
Downtown Greyhound Station
Mesa Bus StopNo tags
Greyhound Lines, Inc.Bus
Downtown Greyhound Station
Mesa Bus StopNo tags
Greyhound Lines, Inc.Bus
537-517 W. Jackson Blvd
Mesa Bus StopNo tags

Last refresh of the prices: Today at 8:30 AM CST.

Get from Chicago to Mesa

This route is served by bus only

The journey takes about 1 day, 21 hours 40 minutes and with fares starting at just $223, it presents an excellent value for a comfortable ride.

5bus per day
1d 21hAverage Duration
1439 milesDistance
58kgCO₂ emissions

Frequently asked questions about traveling from Chicago to Mesa by bus

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
11/19
No data
11/20
$236
Today
No data
11/22
$378
11/23
No data
11/24
No data
11/25
No data
11/26
No data
busbud logoThe cheapest trip from Chicago to Mesa was searched and found on Nov 20, 2025 with a price of $236

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to Mesa, as early as possible.

You can expect to pay from $236 to $462 for a bus ticket from Chicago to Mesa based on the last 2 days. You can expect to find the cheapest price for the trip at $378 which is on 2025-11-22.

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