Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Bus | Chicago 95Th & Dan Ryan | Mesa Bus Stop | Cheapest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Downtown Greyhound Station | Mesa Bus Stop | Fastest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Downtown Greyhound Station | Mesa Bus Stop | No tags | ||||
 | Bus | Downtown Greyhound Station | Mesa Bus Stop | No tags | ||||
| Bus | 537-517 W. Jackson Blvd | Mesa Bus Stop | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Chicago 95Th & Dan Ryan | Mesa Bus Stop | No tags | ||||
| Bus | 537-517 W. Jackson Blvd | Mesa Bus Stop | No tags | ||||
| Bus | Chicago 95Th & Dan Ryan | Mesa Bus Stop | No tags |
Last refresh of the prices: Today at 11:18 AM CDT.
Get from Chicago to Mesa
The journey takes about 1 day, 20 hours 25 minutes and with fares starting at just A$221, it presents an excellent value for a comfortable ride.
Bus stations and stops in Chicago and Mesa
Stops in Chicago
- A
Downtown Greyhound Station
630 W Harrison St, Chicago, IL 60607, USA - C
Polk St & Canal St
500-536 W Polk St, Chicago IL 60607, USA - D
Tornado Bus S Kedzie Ave
2807 S Kedzie Ave, Chicago, IL 60623, USA - E
Cumberland CTA
5800 N Cumberland Ave, Chicago, IL 60631, USA - F
Turimex California Ave
2139 S California Ave, Chicago, IL 60608, USA
Stops in Mesa
- A
Mesa Bus Station
1423 S Country Club , Mesa, AZ 85210, USA
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Chicago to Mesa by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Chicago to Mesa?
The cheapest bus tickets from Chicago to Mesa start from A$221. The average price for this route is around A$328. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Chicago to Mesa?
The average bus trip duration from Chicago to Mesa is 1d 20h, covering a distance of 1438 miles (2319 km). The quickest bus can get you there in 1d 20h and is operated by Greyhound.
Which bus companies service the Chicago to Mesa route?
Several major bus companies operate on this route with 7 buses available per day.
What is the earliest and latest departure time for the bus from Chicago to Mesa?
The earliest bus departs from Chicago to Mesa at 12:15am. And the latest bus departs at 11:45pm.
What are the CO₂ emissions for the bus trip from Chicago to Mesa?
A bus trip from Chicago to Mesa generates an estimated 57.968650000000004 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Chicago to Mesa was searched and found on Aug 3, 2026 with a price of A$427To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to Mesa, as early as possible.
You can expect to pay from A$427 to A$759 for a bus ticket from Chicago to Mesa based on the last 2 days. You can expect to find the cheapest price for the trip at A$427 which is on 2026-08-03.
