Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Cincinnati Bus Station | Knoxville Bus Station | CheapestFastest |
Last refresh of the prices: Last Friday at 9:43 PM EST.
Get from Cincinnati to Knoxville
The journey takes about 5 hours 35 minutes, and with fares starting at just R 751, it presents an excellent value for a comfortable ride.
Where are the popular stops in Cincinnati and Knoxville?
Stops in Cincinnati
- A1005 Gilbert Ave, Cincinnati, OH 45202
- B
Northland Blvd
290-322 Northland Blvd, Springdale, OH 45246, USA
Stops in Knoxville
- AKnoxville Area Transit Bus Stop, 100 Kirkwood St, Knoxville, TN 37914, USA
Compare bus companies
Based on 87391 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. Greyhound ticket prices on this trip start at R 751
Greyhound Cincinnati Knoxville recent customer reviews
30 minute delay plus air conditioner was broken on bus very uncomfortable for my very first bus ride
Jaicelyn T.
Driver was a substitute for absent driver and very apprehensive about anyone approaching or talking with a moderate decibel. Bus felt like the The front was shaking due to an unbalanced tire. When inquiring with the bus driver he said he had to leave the resistant break on from the time we left Lexington until Knoxville
Michael N.
Frequently asked questions about travelling from Cincinnati to Knoxville, TN by bus
How much does a bus ticket from Cincinnati to Knoxville cost?
The bus ticket price from Cincinnati to Knoxville starts at R 751. The best way to find cheap bus tickets from Cincinnati to Knoxville is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the bus ride from Cincinnati to Knoxville?
The average travel time between Cincinnati and Knoxville is around 5h 35m, although the fastest bus will take about 5h 35m. This is the time it takes to travel the 360 km that separates the two cities.
How many daily bus connections are there between Cincinnati and Knoxville?
The number of buses from Cincinnati to Knoxville can differ depending on the day of the week. On average, there are 1 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Cincinnati to Knoxville by comparing and selecting the bus that fits your travel style and budget on Busbud.
Which bus companies travel from Cincinnati to Knoxville?
When taking the bus from Cincinnati to Knoxville, you can travel comfortably and safely with Greyhound.
What are the departure and arrival stations when taking the bus from Cincinnati to Knoxville?
Buses travelling between Cincinnati and Knoxville leave from Greyhound Station or Northland Blvd and arrive at 100 Kirkwood St.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Cincinnati to Knoxville, TN was searched and found on 21 Nov 2025 with a price of R 820To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Cincinnati to Knoxville, TN as early as possible.
You can expect to pay from R 820 to R 1 318 for a bus ticket from Cincinnati to Knoxville, TN based on the last 2 days. You can expect to find the cheapest price for the trip at R 873, which is on 2025-11-27.
