Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Des Moines | Airways Transit Center | CheapestFastest | ||||
 | Bus | Des Moines | Memphis Bus Station | No tags | ||||
| Bus | Des Moines | Airways Transit Center | No tags | ||||
| Bus | Des Moines | Memphis Bus Station | No tags |
Last refresh of the prices: Last Friday at 5:31 PM CST.
Get from Des Moines to Memphis
The journey takes about 22 hours 35 minutes, and with fares starting at just R 2 151, it presents an excellent value for a comfortable ride.
Where are the popular stops in Des Moines and Memphis?
Stops in Des Moines
- A
Jefferson/Trailways Depot
1501 2nd Ave North, Des Moines, IA 50314 - B
1514 East Grand Ave
1514 East Grand Avenue,, Des Moins, IA, 50316
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Frequently asked questions about travelling from Des Moines to Memphis, TN by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Des Moines to Memphis?
The cheapest bus tickets from Des Moines to Memphis start at R 2 151. The average price for this route is around R 2 824. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Des Moines to Memphis?
The average bus journey time from Des Moines to Memphis is 22h 35m, covering a distance of 795 km. The fastest bus gets you there in 16h 25m and is operated by Jefferson Lines.
Which bus companies service the Des Moines to Memphis route?
Several major bus companies operate on this route with 2 buses available per day, including services from Jefferson Lines, Greyhound.
What is the earliest and latest departure time for the bus from Des Moines to Memphis?
The earliest bus departs from Des Moines to Memphis at 00:01. And the latest bus departs at 09:45.
What are the CO₂ emissions for the bus trip from Des Moines to Memphis?
A bus trip from Des Moines to Memphis produces an estimated 20 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
What is the best bus company from Des Moines to Memphis?
According to Busbud customers, the highest-rated bus company on this route is Jefferson Lines, with an average rating of 3.9 out of 5 stars based on 766 reviews.
Which bus company has the best Wi-Fi from Des Moines to Memphis?
Based on reviews on Busbud, the bus company Greyhound has the best Wi-Fi rating with a score of 2.5.
Which bus company offers the most punctual service from Des Moines to Memphis?
According to Busbud traveller reviews, the most punctual bus company on this route is Jefferson Lines, with a punctuality rating of 3.7 out of 5 stars.
Which bus company has the cleanest buses from Des Moines to Memphis?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Jefferson Lines, with a cleanliness rating of 4.4 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Des Moines to Memphis, TN was searched and found on 05 Feb 2026 with a price of R 1 968To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Des Moines to Memphis, TN as early as possible.
You can expect to pay from R 1 968 to R 3 968 for a bus ticket from Des Moines to Memphis, TN based on the last 2 days. You can expect to find the cheapest price for the trip at R 1 968, which is on 2026-02-05.
Usually Jefferson Lines will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
