Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Detroit Bus Station | Knoxville Bus Station | CheapestFastest | ||||
| Bus | Detroit Bus Station | Knoxville Bus Station | No tags | ||||
| Bus | Detroit Bus Station | Knoxville Bus Station | No tags | ||||
| Bus | Detroit Bus Station | Knoxville Bus Station | No tags |
Last refresh of the prices: Yesterday at 9:13 PM EST.
Get from Detroit to Knoxville
The journey takes about 21 hours 25 minutes, and with fares starting at just R 1 142, it presents an excellent value for a comfortable ride.
Where are the popular stops in Detroit and Knoxville?
Stops in Knoxville
- AKnoxville Area Transit Bus Stop, 100 Kirkwood St, Knoxville, TN 37914, USA
Compare bus companies
Based on 87519 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained about the Wi-Fi. Greyhound ticket prices on this trip start at R 1 142
Greyhound Detroit Knoxville recent customer reviews
Very late arrival
Ronell W.
The drivers were awesome. Trip was very comfortable.
Juliana T.
Frequently asked questions about travelling from Detroit, MI to Knoxville, TN by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Detroit to Knoxville?
The cheapest bus tickets from Detroit to Knoxville start at R 1 142. The average price for this route is around R 2 190. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Detroit to Knoxville?
The average bus journey time from Detroit to Knoxville is 21h 25m, covering a distance of 708 km. The fastest bus gets you there in 12h 15m and is operated by Greyhound.
Which bus companies service the Detroit to Knoxville route?
Several major bus companies operate on this route with 4 buses available per day.
What is the earliest and latest departure time for the bus from Detroit to Knoxville?
The earliest bus departs from Detroit to Knoxville at 06:40. And the latest bus departs at 23:25.
What are the CO₂ emissions for the bus trip from Detroit to Knoxville?
A bus trip from Detroit to Knoxville produces an estimated 18 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Detroit, MI to Knoxville, TN was searched and found on 05 Feb 2026 with a price of R 1 156To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Detroit, MI to Knoxville, TN as early as possible.
You can expect to pay from R 1 156 to R 3 483 for a bus ticket from Detroit, MI to Knoxville, TN based on the last 2 days. You can expect to find the cheapest price for the trip at R 1 156, which is on 2026-02-05.
