- Detroit to Knoxville buses
Previously seen journeys
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link | 
|---|---|---|---|---|---|---|---|---|
|  | Detroit Bus Station | Knoxville Bus Station | No tags | |||||
|  | Detroit Bus Station | Knoxville Bus Station | No tags | |||||
|  | Detroit Bus Station | Knoxville Bus Station | No tags | |||||
|  | Detroit Bus Station | Knoxville Bus Station | No tags | |||||
|  | Detroit Bus Station | Knoxville Bus Station | No tags | 
Accepted payments
Get from Detroit to Knoxville
The journey takes about 21 hours 45 minutes, and with fares starting at just US$47, it presents an excellent value for a comfortable ride.
Bus Detroit, MI to Knoxville, TN: Trip Overview
Compare bus companies
Based on 87342 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. Greyhound ticket prices on this trip start at US$47
Greyhound Detroit Knoxville recent customer reviews
Very late arrival
Ronell W.
The drivers were awesome. Trip was very comfortable.
Juliana T.
Detroit to Knoxville Bus
Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Detroit to Knoxville.
We make it our job to connect you with the most dependable bus companies that cover bus service from Detroit to Knoxville.
From cheap bus tickets to more luxurious buses travelling from Detroit to Knoxville, we offer a wide range of bus services to best suit your needs depending on how much your budget is.
Where are the popular stops in Detroit and Knoxville?
Frequently asked questions on the trip Detroit, MI - Knoxville, TN
- How much does a bus ticket from Detroit to Knoxville cost?- The bus ticket price from Detroit to Knoxville starts at US$47. The best way to find cheap bus tickets from Detroit to Knoxville is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices! 
- How long is the bus ride from Detroit to Knoxville?- The average travel time between Detroit and Knoxville is around 21h 45m, although the fastest bus will take about 12h 15m. This is the time it takes to travel the 714 km that separates the two cities. 
- How many daily bus connections are there between Detroit and Knoxville?- The number of buses from Detroit to Knoxville can differ depending on the day of the week. On average, there are 4 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Detroit to Knoxville by comparing and selecting the bus that fits your travel style and budget on Busbud. 
- Which bus companies travel from Detroit to Knoxville?- When taking the bus from Detroit to Knoxville, you can travel comfortably and safely with Greyhound. 
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Detroit, MI to Knoxville, TN as early as possible.
You can expect to pay from US$50 to US$61 for a bus ticket from Detroit, MI to Knoxville, TN based on the last 2 days. You can expect to find the cheapest price for the trip at US$54, which is on 2025-10-31.
About Bus Travel
Bus Travel Tips
If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Detroit to Knoxville but it'll also be endearing to native speakers who will surely appreciate your effort.
From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Detroit to Knoxville.
Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Detroit to Knoxville that are otherwise impossible to come by with a plane.
Tune out to the fine sounds of your best music playlist on your bus trip from Detroit to Knoxville while indulging in miles on end of beautiful scenic views.
Did you know?
9.2% of ground transportation in Europe is done by bus versus 7.4% by train.
The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
Top travelled bus routes
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Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.
People from around the world trust Busbud
Popular Buses Connecting Detroit
Buses Leaving from Detroit
- Bus from Detroit to Marathon
- Coach Detroit - Miami
- Bus Detroit - Miami
- Bus from Detroit to Boston
- Coach Detroit - Ann Arbor
- Bus Detroit - Niagara Falls
- Bus from Detroit to Wildwood
- Coach Detroit - State College
- Bus Detroit - Abilene
- Bus from Detroit to Kankakee
- Coach Detroit - Brownsville
- Bus Detroit - Reading
- Bus from Detroit to San Bernardino
- Coach Detroit - Fayetteville
- Bus Detroit - Lafayette
Buses Going to Detroit
- Bus from Toronto to Detroit
- Coach Nashville - Detroit
- Bus Windsor - Detroit
- Bus from Olympia to Detroit
- Coach Buffalo - Detroit
- Bus Dearborn - Detroit
- Bus from Valparaiso to Detroit
- Coach Bellingham - Detroit
- Bus White River Junction - Detroit
- Bus from Indio to Detroit
- Coach Rockford - Detroit
- Bus Wichita Falls - Detroit
- Bus from Mobile to Detroit
- Coach Pecos - Detroit
- Bus Hickory - Detroit
Popular Buses Connecting Knoxville
Buses Leaving from Knoxville
- Bus from Knoxville to Charlotte
- Coach Knoxville - Marathon
- Bus Knoxville - Lexington
- Bus from Knoxville to Orlando
- Coach Knoxville - Chicago
- Bus Knoxville - Greenville
- Bus from Knoxville to Longview
- Coach Knoxville - Athens
- Bus Knoxville - Van Buren
- Bus from Knoxville to Lawrence
- Coach Knoxville - Warner Robins
- Bus Knoxville - Ithaca
- Bus from Knoxville to Akron
- Coach Knoxville - Savannah
- Bus Knoxville - Joplin
Buses Going to Knoxville
- Bus from Nashville to Knoxville
- Coach Memphis - Knoxville
- Bus Charlotte - Knoxville
- Bus from Chicago to Knoxville
- Coach Tampa - Knoxville
- Bus Detroit - Knoxville
- Bus from Rockford to Knoxville
- Coach Easton - Knoxville
- Bus Deming - Knoxville
- Bus from Spartanburg to Knoxville
- Coach Portsmouth - Knoxville
- Bus Jacksonville - Knoxville
- Bus from Lansing to Knoxville
- Coach Naples - Knoxville
- Bus Athens - Knoxville
Popular routes in this country
- Bus from Buffalo to Niagara Falls
- Coach Houston - Brownsville
- Bus New York City - Fleischmanns
- Bus from Miami to Orlando
- Coach Newark - Norfolk
- Bus Milwaukee - Appleton
- Bus from New York City to Pittsburgh
- Coach Harrisonburg - Blacksburg
- Bus Alexandria - Charlottesville
- Bus from Norfolk to Newark
- Coach Hartford - New York City
- Bus Rancho Cucamonga - Los Angeles
- Bus from Brownsville to Houston





