Find coaches from Durham, NC, US to Florence, SC, US

Next departures

Next departures from Durham to Florence on 5 November
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus
    		Durham Greyhound Bus Station
    		Bus stationCheapest
    Wanda Coach
      		BP Gas Station
      		2301 W Lucas St.Fastest

      Last refresh of the prices: Last Friday at 9:02 PM EDT.

      Accepted payments

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      Compare 2 ways to travel from Durham to Florence

      We recommend taking the bus

      Among the sustainable travel choices, the bus stands out as a good way to reach Florence. The journey takes about 3 hours 40 minutes and with fares starting at just US$34, it presents an excellent value for a comfortable ride.

      1bus per day
      3h 40mAverage duration
      215 kmDistance
      5kgCO₂ emissions
      Bus
      		Average priceUS$34 - US$67Average duration3h 40m
      5kg CO₂e
      Train
      		Average priceUS$47 - US$70Average duration8h 25m
      20kg CO₂e

      Bus Durham, NC, US to Florence, SC, US: Trip Overview

      Average ticket priceUS$67
      Average bus trip duration3h 40m
      Number of daily buses1
      Earliest bus departure04:20
      Distance215 km
      Latest bus departure21:15

      Durham to Florence Bus

      Busbud helps you find a bus from Durham to Florence. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

      We make sure you can find a bus service from Durham to Florence from the most reliable bus companies operating this trip.

      Whether it is cheap bus tickets or more luxurious buses going to Florence from Durham, we help you find what you're looking for based on how much of a budget you have.

      Frequently asked questions on the trip Durham, NC, US - Florence, SC, US

      1. How much does a bus ticket from Durham to Florence cost?

        The bus ticket price from Durham to Florence starts at US$34. The best way to find cheap bus tickets from Durham to Florence is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

      2. How long is the bus ride from Durham to Florence?

        The average travel time between Durham and Florence is around 3h 40m, although the fastest bus will take about 3h 40m. This is the time it takes to travel the 210 km that separates the two cities.

      3. How many daily bus connections are there between Durham and Florence?

        The number of buses from Durham to Florence can differ depending on the day of the week. On average, there are 1 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Durham to Florence by comparing and selecting the bus that fits your travel style and budget on Busbud.

      4. Which bus companies travel from Durham to Florence?

        When taking the bus from Durham to Florence, you can travel comfortably and safely with FlixBus, Wanda Coach.

      5. What are the departure and arrival stations when taking the bus from Durham to Florence?

        Buses travelling between Durham and Florence leave from Durham Greyhound Bus Station or Compare Foods Durham and arrive at Florence Bus Station, TA Travel Center - Florence.

      Find cheapest prices for buses

      Price is for a one-way ticket for one passenger and based on past searches.

      Best price found
      31/10
      US$30
      01/11
      No data
      Today
      No data
      03/11
      No data
      04/11
      No data
      05/11
      US$27
      06/11
      US$26
      07/11
      US$28
      busbud logoThe cheapest trip from Durham, NC, US to Florence, SC, US was searched and found on 06 Nov 2025 with a price of US$26

      To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Durham, NC, US to Florence, SC, US as early as possible.

      You can expect to pay from US$26 to US$60 for a bus ticket from Durham, NC, US to Florence, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at US$26, which is on 2025-11-06.

      Usually Wanda Coach will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

      About Bus Travel

      Bus Travel Tips

      Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Durham and Florence!

      Start sightseeing the minute your bus leaves the station. If you're on the night bus from Durham to Florence, get comfy and count the stars.

      Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Durham to Florence.

      Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Durham to Florence.

      Did you know?

      It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

      The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

      The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

      What's the cheapest way to go from Durham, NC, US to Florence, SC, US?

      busbud logoThe bus is the cheapest travel choice for this destination

      Will you be returning to Durham, NC, US by bus?

      Bus from Florence, SC, US to Durham, NC, US

      You can also go to Florence, SC, US by train

      Train from Durham, NC, US to Florence, SC, US

      Why choose Busbud?

      The Best Way To Book Bus and Train Tickets

      Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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