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- This trip is recommended because it is the: Cheapest + FastestDeparture time: 19 July atDeparture city: DurhamDeparture location: BP Gas StationArrival time: 19 July atDestination city: FlorenceDestination location: 2301 W Lucas St.Operated by: Wanda Coach
Vehicle: BusDuration: - Departure time: 19 July atDeparture city: DurhamDeparture location: Durham Greyhound Bus StationArrival time: 20 July atDestination city: FlorenceDestination location: Florence, SCOperated by: FlixBus
Vehicle: BusDuration:
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Compare 2 ways to travel from Durham to Florence
Busbud recommends taking the bus from Durham to FlorenceAmong the sustainable travel choices, the bus stands out as a good way to reach Florence. The journey takes about 3 hours 40 minutes and with fares starting at just US$38, it presents an excellent value for a comfortable ride.
Bus Durham to Florence: Trip Overview
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Durham to Florence Bus
Busbud helps you find a bus from Durham to Florence. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
We make sure you can find a bus service from Durham to Florence from the most reliable bus companies operating this trip.
Whether it is cheap bus tickets or more luxurious buses going to Florence from Durham, we help you find what you're looking for based on how much of a budget you have.
Where are the popular stops in Durham and Florence?
Frequently asked questions on the trip Durham, NC, US - Florence, SC, US
How far is Florence from Durham by coach?
The distance between Durham and Florence by coach is approximately 131 miles (210 km).
Is there a way to reach Florence from Durham without a car?
The best way to go from Durham to Florence without a car is by coach. They are frequent and reliable, offering a convenient and eco-friendly journey. Depending on your preferences, carpooling can also be considered as an option.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Durham to Florence was searched and found on 16 Jul 2025 with a price of US$38To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Durham to Florence as early as possible.
You can expect to pay from US$38 to US$69 for a bus ticket from Durham to Florence based on the last 2 days. You can expect to find the cheapest price for the trip at US$60, which is on 2025-07-19.
Usually FlixBus Inc. will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Durham and Florence!
Start sightseeing the minute your bus leaves the station. If you're on the night bus from Durham to Florence, get comfy and count the stars.
Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Durham to Florence.
Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Durham to Florence.
Did you know?
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.
The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!
What's the cheapest way to go from Durham to Florence?
The bus is the cheapest travel choice for this destinationTop travelled bus routes
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