Next bus departures

Next departures for Durham to Florence on September 23
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Bus Wifi Toilet Power outlets	9:10am	Durham	7h 45m	4:55pm	Bus station	CheapestFastest

Next departures for Durham to Florence on September 24
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus Wifi Toilet Power outlets	9:15pm	Durham	8h 30m	5:45am	Florence, SC	Cheapest
Bus Wifi Power outlets	4:20am	BP Gas Station	3h 40m	8:00am	2301 W Lucas St.	Fastest
Bus Wifi Toilet Power outlets	9:10am	Durham	7h 45m	4:55pm	Bus station	No tags

Last refresh of the prices: Last Monday at 2:59 PM EDT.

Compare 2 ways to go from Durham to Florence

We recommend taking the bus

Among the sustainable travel choices, the Bus stands out as a good way to reach Florence. The journey takes about 7 hours 45 minutes and with fares starting at just MAD 399, it presents an excellent value for a comfortable ride.

2bus per day

7h 45mAverage Duration

134 milesDistance

5kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average PriceMAD 399 - MAD 722	Average Duration7h 45m	CO₂ emissions 5kg CO₂e
Train	Average PriceMAD 509 - MAD 732	Average Duration10h 51m	CO₂ emissions 20kg CO₂e

Bus stations and stops in Durham and Florence

Stops in Durham

A
Durham Greyhound Bus Station
515 W Pettigrew St , Durham, NC 27703
Visit page
B
Compare Foods Durham
2000-2004 NC-55, Durham, NC 27704, USA
C
Durham Compare Foods Durham
2000 Avondale Dr, Durham, NC 27704, USA
D
Durham, NC
E Main St at Roxboro St (WB), Durham, NC 27701, USA

Stops in Florence

A
Florence Bus Station
619 S Irby St, Florence, SC 29501, USA
Visit page
B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA

Compare bus companies

FlixBus

3.5/515,843 reviews

Staff4.2

Timeliness4.0

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

Greyhound

3.5/588,163 reviews

Staff3.6

Timeliness3.0

Cleanliness3.4

Wifi2.5

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

Wanda Coach

2.6/5778 reviews

Staff2.9

Timeliness2.8

Cleanliness2.5

Wifi1.6

Wanda Coach is one of the main Chinatown bus carriers in the US, connecting about 75 cities around the country with inexpensive tickets and comfortable bus rides. Wanda Coach buses travel between Chinatown neighborhoods with direct buses that are affordable, safe and have convenient pick-up and drop-off locations. If you travel with Wanda Coach, you can reschedule your tickets for a $10 fee up to 2 hours before travel time, and their buses have free WiFi, power outlets and bathrooms.

US bus companies:FlixBus, Greyhound, Futura, Tufesa, Chihuahuenses, Adirondack Trailways, Valley Transit

Frequently asked questions about traveling from Durham, NC, US to Florence, SC, US by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Durham to Florence?
The cheapest bus tickets from Durham to Florence start from MAD 399. The average price for this route is around MAD 589. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Durham to Florence?
The average bus trip duration from Durham to Florence is 7h 45m, covering a distance of 134 miles (216 km). The quickest bus can get you there in 3h 40m and is operated by Wanda Coach.
Which bus companies service the Durham to Florence route?
Several major bus companies operate on this route with 2 buses available per day, including services from FlixBus, Greyhound, Wanda Coach.
What is the earliest and latest departure time for the bus from Durham to Florence?
The earliest bus departs from Durham to Florence at 4:20am. And the latest bus departs at 9:15pm.
What are the CO₂ emissions for the bus trip from Durham to Florence?
A bus trip from Durham to Florence generates an estimated 5.380199999999999 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Durham to Florence?
According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 15599 reviews.
Which bus company has the best Wi-Fi from Durham to Florence?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Durham to Florence?
According to Busbud traveler reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 4.0 out of 5 stars.
Which bus company has the cleanest buses from Durham to Florence?
According to Busbud traveler reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

09/21

No data

09/22

MAD 475

Today

MAD 461

09/24

MAD 328

09/25

No data

09/26

No data

09/27

No data

09/28

No data

The cheapest trip from Durham, NC, US to Florence, SC, US was searched and found on Sep 24, 2026 with a price of MAD 328

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Durham, NC, US to Florence, SC, US, as early as possible.

You can expect to pay from MAD 328 to MAD 583 for a bus ticket from Durham, NC, US to Florence, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at MAD 328 which is on 2026-09-24.