Bus Tickets from Durham, NC, US to Florence, SC, US

Next departures

Next departures for Durham to Florence on October 6
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Wanda Coach
BP Gas Station
2301 W Lucas St.CheapestFastest

Last refresh of the prices: Today at 2:13 PM EDT.

Accepted payments

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Compare 2 ways to go from Durham to Florence.

Bus
Average Price$38 - $92Average Duration3h 40m
5kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average Price$47 - $76Average Duration8h 25m
20kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Durham to Florence

Among the sustainable travel choices, the bus stands out as the good way to reach Florence. The journey takes about 3 hours 40 minutes and with fares starting at just $38, it presents an excellent value for a comfortable ride.

1bus per day
3h 40mAverage Duration
$38Cheapest ticket
5kgCO₂ emissions

Bus Durham, NC, US to Florence, SC, US: Trip Overview

Average ticket price$67
Average bus trip duration3h 40m
Number of daily buses1
Earliest bus departure4:20am
Distance134 miles (215 km)
Latest bus departure9:15pm

Durham to Florence Bus

Busbud helps you find a bus from Durham to Florence. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Durham to Florence from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to Florence from Durham, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions for your trip Durham, NC, US - Florence, SC, US

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
10/03
$38
10/04
No data
Today
$40
10/06
$60
10/07
No data
10/08
No data
10/09
No data
10/10
No data
busbud logoThe cheapest trip from Durham, NC, US to Florence, SC, US was searched and found on Oct 3, 2025 with a price of $38

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Durham, NC, US to Florence, SC, US, as early as possible.

You can expect to pay from $38 to $60 for a bus ticket from Durham, NC, US to Florence, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at $60 which is on 2025-10-06.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Durham and Florence!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Durham to Florence, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Durham to Florence.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Durham to Florence.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

What's the cheapest way to go from Durham, NC, US to Florence, SC, US?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Durham, NC, US by bus?

Bus from Florence, SC, US to Durham, NC, US

You can also go to Florence, SC, US by train

Train from Durham, NC, US to Florence, SC, US

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With several language and currency options available, Busbud seeks to cater to international bus travelers no matter where they are in the world. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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