Find coaches from Durham, NC, US to Greenville, SC

Next departures

Next departures from Durham to Greenville on 3 November
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus
    		Durham Greyhound Bus Station
    		1116 Woodruff RdCheapestFastest

    Last refresh of the prices: Yesterday at 6:27 PM EST.

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    Compare 2 ways to travel from Durham to Greenville

    We recommend taking the bus

    Among the sustainable travel choices, the bus stands out as a good way to reach Greenville. The journey takes about 4 hours 45 minutes and with fares starting at just US$41, it presents an excellent value for a comfortable ride.

    9bus per day
    4h 45mAverage duration
    335 kmDistance
    8kgCO₂ emissions
    Bus
    		Average priceUS$41 - US$153Average duration4h 45m
    8kg CO₂e
    Train
    		Average priceUS$67 - US$106Average duration11h 20m
    31kg CO₂e

    Bus Durham, NC, US to Greenville, SC: Trip Overview

    Average ticket priceUS$56
    Average bus trip duration4h 45m
    Number of daily buses9
    Earliest bus departure01:30
    Distance334 km
    Latest bus departure14:50

    Durham to Greenville Bus

    Busbud helps you find a bus from Durham to Greenville. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

    We make it our job to connect you with the most dependable bus companies that cover bus service from Durham to Greenville.

    Whether it is cheap bus tickets or more luxurious buses going to Greenville from Durham, we help you find what you're looking for based on how much of a budget you have.

    Frequently asked questions on the trip Durham, NC, US - Greenville, SC

    1. How much does a bus ticket from Durham to Greenville cost?

      The bus ticket price from Durham to Greenville starts at US$41. The best way to find cheap bus tickets from Durham to Greenville is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

    2. How long is the bus ride from Durham to Greenville?

      The average travel time between Durham and Greenville is around 4h 45m, although the fastest bus will take about 4h 30m. This is the time it takes to travel the 342 km that separates the two cities.

    3. How many daily bus connections are there between Durham and Greenville?

      The number of buses from Durham to Greenville can differ depending on the day of the week. On average, there are 9 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Durham to Greenville by comparing and selecting the bus that fits your travel style and budget on Busbud.

    4. Which bus companies travel from Durham to Greenville?

      When taking the bus from Durham to Greenville, you can travel comfortably and safely with FlixBus, Wanda Coach, Tornado Bus.

    5. What are the departure and arrival stations when taking the bus from Durham to Greenville?

      Buses travelling between Durham and Greenville leave from Durham Greyhound Bus Station or Compare Foods Durham and arrive at Guadalajara Supermarket Bus Stop, Greenville Bus Station.

    Find cheapest prices for buses

    Price is for a one-way ticket for one passenger and based on past searches.

    Best price found
    01/11
    US$41
    02/11
    US$42
    Today
    US$48
    04/11
    No data
    05/11
    No data
    06/11
    No data
    07/11
    No data
    08/11
    No data
    busbud logoThe cheapest trip from Durham, NC, US to Greenville, SC was searched and found on 01 Nov 2025 with a price of US$41

    To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Durham, NC, US to Greenville, SC as early as possible.

    About Bus Travel

    Bus Travel Tips

    Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Durham and Greenville!

    From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Durham to Greenville.

    Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Durham to Greenville.

    Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Durham to Greenville.

    Did you know?

    The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

    One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

    The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

    What's the cheapest way to go from Durham, NC, US to Greenville, SC?

    busbud logoThe bus is the cheapest travel choice for this destination

    Will you be returning to Durham, NC, US by bus?

    Bus from Greenville, SC to Durham, NC, US

    You can also go to Greenville, SC by train

    Train from Durham, NC, US to Greenville, SC

    Why choose Busbud?

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    Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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