Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Bus | Frederick | Chicago 95Th & Dan Ryan | Cheapest | ||||
 | Bus | Frederick | Downtown Greyhound Station | Fastest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Frederick | Downtown Greyhound Station | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Frederick | 537-517 W. Jackson Blvd | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Frederick | Chicago 95Th & Dan Ryan | No tags |
Last refresh of the prices: Last Wednesday at 6:26 PM EST.
Get from Frederick to Chicago
The journey takes about 20 hours 45 minutes, and with fares starting at just R 1 243, it presents an excellent value for a comfortable ride.
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Frequently asked questions about travelling from Frederick to Chicago by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Frederick to Chicago?
The cheapest bus tickets from Frederick to Chicago start at R 1 243. The average price for this route is around R 1 749. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Frederick to Chicago?
The average bus journey time from Frederick to Chicago is 20h 45m, covering a distance of 906 km. The fastest bus gets you there in 15h 25m and is operated by Greyhound.
Which bus companies service the Frederick to Chicago route?
What is the earliest and latest departure time for the bus from Frederick to Chicago?
The earliest bus departs from Frederick to Chicago at 05:05. And the latest bus departs at 19:35.
What are the CO₂ emissions for the bus trip from Frederick to Chicago?
A bus trip from Frederick to Chicago produces an estimated 23 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
What is the best bus company from Frederick to Chicago?
According to Busbud customers, the highest-rated bus company on this route is Amtrak, with an average rating of 4.1 out of 5 stars based on 5759 reviews.
Which bus company has the best Wi-Fi from Frederick to Chicago?
Based on reviews on Busbud, the bus company Amtrak has the best Wi-Fi rating with a score of 3.6.
Which bus company offers the most punctual service from Frederick to Chicago?
According to Busbud traveller reviews, the most punctual bus company on this route is Amtrak, with a punctuality rating of 3.8 out of 5 stars.
Which bus company has the cleanest buses from Frederick to Chicago?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Amtrak, with a cleanliness rating of 4.5 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Frederick to Chicago was searched and found on 01 Mar 2026 with a price of R 1 567To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Frederick to Chicago as early as possible.
You can expect to pay from R 1 567 to R 1 877 for a bus ticket from Frederick to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at R 1 567, which is on 2026-03-01.
