Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Bus | Frederick | Chicago 95Th & Dan Ryan | Cheapest | ||||
 | Bus | Frederick | Downtown Greyhound Station | Fastest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Frederick | Downtown Greyhound Station | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Frederick | 537-517 W. Jackson Blvd | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Frederick | Chicago 95Th & Dan Ryan | No tags |
Last refresh of the prices: Yesterday at 6:26 PM EST.
Get from Frederick to Chicago
The journey takes about 20 hours 45 minutes, and with fares starting at just $107, it presents an excellent value for a comfortable ride.
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Frequently asked questions about travelling from Frederick to Chicago by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Frederick to Chicago?
The cheapest bus tickets from Frederick to Chicago start from $107. The average price for this route is around $151. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Frederick to Chicago?
The average bus travel time from Frederick to Chicago is 20h 45m, covering a distance of 906 km. The quickest bus can get you there in 15h 25m and is operated by Greyhound.
Which bus companies service the Frederick to Chicago route?
What are the earliest and latest departure times for the bus from Frederick to Chicago?
The earliest bus departs from Frederick to Chicago at 5:05am. And the latest bus departs at 7:35pm.
What are the CO₂ emissions for the bus trip from Frederick to Chicago?
A bus trip from Frederick to Chicago generates an estimated 23 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Frederick to Chicago?
According to Busbud customers, the highest-rated bus company on this route is Amtrak, with an average rating of 4.1 out of 5 stars based on 5759 reviews.
Which bus company has the best Wi-Fi from Frederick to Chicago?
Based on Busbud reviews, the bus company Amtrak has the highest Wi-Fi rating with a score of 3.6.
Which bus company has the best on-time performance from Frederick to Chicago?
According to Busbud traveller reviews, the most punctual bus company on this route is Amtrak, with a punctuality rating of 3.8 out of 5 stars.
Which bus company has the cleanest buses from Frederick to Chicago?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Amtrak, with a cleanliness rating of 4.5 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Frederick to Chicago was searched and found on Mar 1, 2026 with a price of $135To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Frederick to Chicago, as early as possible.
You can expect to pay from $135 to $162 for a bus ticket from Frederick to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at $135 which is on 2026-03-01.
