Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Guaymas | Mexicali Central Bus Station, Avenida Francisco Sarabia 1298, Mexicali | Cheapest | ||||
 | Bus | Guaymas | Tufesa | Fastest | ||||
| Bus | Guaymas | Tufesa | No tags | ||||
 | Bus | Guaymas | Mexicali Central Bus Station, Avenida Francisco Sarabia 1298, Mexicali | No tags | ||||
| Bus | Guaymas | Tufesa | No tags |
Last refresh of the prices: Last Friday at 3:41 PM MST.
Get from Guaymas to Mexicali
The journey takes about 12 hours, and with fares starting at just R 1 424, it presents an excellent value for a comfortable ride.
Where are the popular stops in Guaymas and Mexicali?
Stops in Guaymas
- A
Terminal TAP de Guaymas
Calzada Agustín García López #915, Colonia Delicias, 85440 Guaymas
Stops in Mexicali
- A
Terminal de Autobuses de Mexicali
Calzada Independencia No. 1244 (entre Blvd. Anahuac y Lopez Mateos, Col. Centro Civico), 21000 Mexicali - B
Nuevo Mexicali
Blvd. Lázaro Cárdenas 2666 -1 , Fraccionamiento, Col. Nuevo Mexicali - CMéxico 2, Puebla, 21620 Puebla, B.C., Mexico
- D
Apozol Central 27
Apozol Central 27, Zacatecas, Mexicali, B.C., Mexico - E
Bvld Lázaro Cárdenas
Blvrd Lázaro Cárdenas #3295, Mexicali, B.C., Mexico
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Frequently asked questions about travelling from Guaymas to Mexicali by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Guaymas to Mexicali?
The cheapest bus tickets from Guaymas to Mexicali start at R 1 424. The average price for this route is around R 1 580. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Guaymas to Mexicali?
The average bus journey time from Guaymas to Mexicali is 12h, covering a distance of 683 km. The fastest bus gets you there in 10h 35m and is operated by Tufesa.
Which bus companies service the Guaymas to Mexicali route?
Several major bus companies operate on this route with 7 buses available per day, including services from Tufesa, Aguacaliente.
What is the earliest and latest departure time for the bus from Guaymas to Mexicali?
The earliest bus departs from Guaymas to Mexicali at 17:30. And the latest bus departs at 23:00.
What are the CO₂ emissions for the bus trip from Guaymas to Mexicali?
A bus trip from Guaymas to Mexicali produces an estimated 17 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
What is the best bus company from Guaymas to Mexicali?
According to Busbud customers, the highest-rated bus company on this route is Tufesa, with an average rating of 3.4 out of 5 stars based on 696 reviews.
Which bus company has the best Wi-Fi from Guaymas to Mexicali?
Based on reviews on Busbud, the bus company Tufesa has the best Wi-Fi rating with a score of 3.0.
Which bus company offers the most punctual service from Guaymas to Mexicali?
According to Busbud traveller reviews, the most punctual bus company on this route is Tufesa, with a punctuality rating of 2.7 out of 5 stars.
Which bus company has the cleanest buses from Guaymas to Mexicali?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Tufesa, with a cleanliness rating of 4.0 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Guaymas to Mexicali was searched and found on 13 Dec 2025 with a price of R 1 203To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Guaymas to Mexicali as early as possible.
You can expect to pay from R 1 203 to R 1 520 for a bus ticket from Guaymas to Mexicali based on the last 2 days. You can expect to find the cheapest price for the trip at R 1 203, which is on 2025-12-15.
Usually Tufesa will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
