Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Guaymas | Mexicali Central Bus Station, Avenida Francisco Sarabia 1298, Mexicali | Cheapest | ||||
 | Bus | Guaymas | Tufesa | Fastest | ||||
| Bus | Guaymas | Tufesa | No tags | ||||
 | Bus | Guaymas | Mexicali Central Bus Station, Avenida Francisco Sarabia 1298, Mexicali | No tags | ||||
| Bus | Guaymas | Tufesa | No tags |
Last refresh of the prices: Yesterday at 4:56 PM MST.
Get from Guaymas to Mexicali
The journey takes about 12 hours 5 minutes, and with fares starting at just $98, it presents an excellent value for a comfortable ride.
Where are the popular stops in Guaymas and Mexicali?
Stops in Guaymas
- A
Terminal TAP de Guaymas
Calzada Agustín García López #915, Colonia Delicias, 85440 Guaymas
Stops in Mexicali
- A
Terminal de Autobuses de Mexicali
Calzada Independencia No. 1244 (entre Blvd. Anahuac y Lopez Mateos, Col. Centro Civico), 21000 Mexicali - B
Nuevo Mexicali
Blvd. Lázaro Cárdenas 2666 -1 , Fraccionamiento, Col. Nuevo Mexicali - CMéxico 2, Puebla, 21620 Puebla, B.C., Mexico
- D
Apozol Central 27
Apozol Central 27, Zacatecas, Mexicali, B.C., Mexico - E
Bvld Lázaro Cárdenas
Blvrd Lázaro Cárdenas #3295, Mexicali, B.C., Mexico
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Frequently asked questions about travelling from Guaymas to Mexicali by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Guaymas to Mexicali?
The cheapest bus tickets from Guaymas to Mexicali start from $98. The average price for this route is around $127. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Guaymas to Mexicali?
The average bus travel time from Guaymas to Mexicali is 12h 5m, covering a distance of 678 km. The quickest bus can get you there in 10h 35m and is operated by Tufesa.
Which bus companies service the Guaymas to Mexicali route?
Several major bus companies operate on this route with 10 buses available per day, including services from Tufesa, Aguacaliente, ABC.
What are the earliest and latest departure times for the bus from Guaymas to Mexicali?
The earliest bus departs from Guaymas to Mexicali at 12:45am. And the latest bus departs at 11:00pm.
What are the CO₂ emissions for the bus trip from Guaymas to Mexicali?
A bus trip from Guaymas to Mexicali generates an estimated 17 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Guaymas to Mexicali?
According to Busbud customers, the highest-rated bus company on this route is Tufesa, with an average rating of 3.4 out of 5 stars based on 700 reviews.
Which bus company has the best Wi-Fi from Guaymas to Mexicali?
Based on Busbud reviews, the bus company Tufesa has the highest Wi-Fi rating with a score of 3.0.
Which bus company has the best on-time performance from Guaymas to Mexicali?
According to Busbud traveller reviews, the most punctual bus company on this route is ABC, with a punctuality rating of 3.8 out of 5 stars.
Which bus company has the cleanest buses from Guaymas to Mexicali?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Tufesa, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Guaymas to Mexicali was searched and found on Jan 10, 2026 with a price of $105To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Guaymas to Mexicali, as early as possible.
You can expect to pay from $105 to $127 for a bus ticket from Guaymas to Mexicali based on the last 2 days. You can expect to find the cheapest price for the trip at $105 which is on 2026-01-12.
Usually Tufesa will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
