Previously seen journeys
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound | Bus | Indianapolis Bus Station | Syracuse (Regional Transportation Center) | No tags | ||||
FlixBus + Greyhound | Bus | Downtown Transit Center | Syracuse (Regional Transportation Center) | No tags | ||||
Greyhound + FlixBus | Bus | Indianapolis Northeast | Syracuse (Regional Transportation Center) | No tags | ||||
FlixBus + Greyhound | Bus | Indianapolis Northeast | Syracuse (Regional Transportation Center) | No tags | ||||
 | Bus | Indianapolis Bus Station | Syracuse (Regional Transportation Center) | No tags |
Compare 2 ways to travel from Indianapolis to Syracuse
Among the sustainable travel choices, the bus stands out as a good way to reach Syracuse. The journey takes about 20 hours 55 minutes and with fares starting at just R 1 733, it presents an excellent value for a comfortable ride.
Where are the popular stops in Indianapolis and Syracuse?
Stops in Syracuse
- A
Regional Transportation Center
1 Walsh Circle Ste 30, Syracuse, NY 13208 - B
Syracuse Airport
- CBus stops at Schine Student Center across the street from the Sheraton Parking Garage., Schine Student Center, 303 University Pl, Syracuse, NY 13210
- D
Syracuse University - Lyman Hall
College Place, Syracuse, NY 13210, USA - E
New York State Fairgrounds
581 State Fair Blvd, Syracuse, NY 13209, USA - F
Syracuse, NY
349-399 US-11, Syracuse, NY 13202, USA
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Frequently asked questions about travelling from Indianapolis to Syracuse, US by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Indianapolis to Syracuse?
The cheapest bus tickets from Indianapolis to Syracuse start at R 1 733. The average price for this route is around R 2 638. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Indianapolis to Syracuse?
The average bus journey time from Indianapolis to Syracuse is 20h 55m, covering a distance of 910 km. The fastest bus gets you there in 20h 30m and is operated by FlixBus.
Which bus companies service the Indianapolis to Syracuse route?
What is the earliest and latest departure time for the bus from Indianapolis to Syracuse?
The earliest bus departs from Indianapolis to Syracuse at 00:15. And the latest bus departs at 23:30.
What are the CO₂ emissions for the bus trip from Indianapolis to Syracuse?
A bus trip from Indianapolis to Syracuse produces an estimated 23 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
What is the best bus company from Indianapolis to Syracuse?
According to Busbud customers, the highest-rated bus company on this route is Amtrak, with an average rating of 4.1 out of 5 stars based on 5597 reviews.
Which bus company has the best Wi-Fi from Indianapolis to Syracuse?
Based on reviews on Busbud, the bus company Amtrak has the best Wi-Fi rating with a score of 3.6.
Which bus company offers the most punctual service from Indianapolis to Syracuse?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Indianapolis to Syracuse?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Amtrak, with a cleanliness rating of 4.5 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Indianapolis to Syracuse, US was searched and found on 30 Nov 2025 with a price of R 1 914To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Indianapolis to Syracuse, US as early as possible.
You can expect to pay from R 1 914 to R 12 577 for a bus ticket from Indianapolis to Syracuse, US based on the last 2 days. You can expect to find the cheapest price for the trip at R 1 914, which is on 2025-11-30.
Usually Amtrak will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Indianapolis to Syracuse, US?
The bus is the cheapest travel choice for this destination
