Find coaches from Indianapolis to Syracuse, US

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Today6 Jul
Tomorrow7 Jul
from US$158
Tue8 Jul
Wed9 Jul
Thu10 Jul
Fri11 Jul
Sat12 Jul
Sun13 Jul

Next departures to Syracuse

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: 7 July at
    Departure city: Indianapolis
    Departure location: Downtown Transit Center
    Arrival time: 8 July at
    Destination city: Syracuse
    Destination location: Syracuse (Regional Transportation Center)
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: 7 July at
    Departure city: Indianapolis
    Departure location: Downtown Transit Center
    Arrival time: 7 July at
    Destination city: Syracuse
    Destination location: Syracuse (Regional Transportation Center)
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 7 July at
    Departure city: Indianapolis
    Departure location: Greyhound Amtrak Station
    Arrival time: 8 July at
    Destination city: Syracuse
    Destination location: SYR Airport
    Operated by: AmtrakAmtrak
    Vehicle: BusDuration:
  • Departure time: 7 July at
    Departure city: Indianapolis
    Departure location: Indianapolis Bus Station
    Arrival time: 8 July at
    Destination city: Syracuse
    Destination location: Syracuse (Regional Transportation Center)
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 7 July at
    Departure city: Indianapolis
    Departure location: Downtown Transit Center
    Arrival time: 7 July at
    Destination city: Syracuse
    Destination location: Syracuse (Regional Transportation Center)
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Compare 2 ways to travel from Indianapolis to Syracuse

Bus
Average priceUS$74 - US$253Average duration22h 25m
23kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average priceUS$195 - US$1,084Average duration1d 5h
83kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Indianapolis to Syracuse

Among the sustainable travel choices, the bus stands out as a good way to reach Syracuse. The journey takes about 22 hours 25 minutes and with fares starting at just US$74, it presents an excellent value for a comfortable ride.

5bus per day
22h 25mAverage duration
US$74Cheapest ticket
23kgCO₂ emissions

Bus Indianapolis to Syracuse: Trip Overview

Average ticket priceUS$156
Average bus trip duration22h 25m
Number of daily buses5
Earliest bus departure00:20
Distance564 miles
Latest bus departure23:30

Indianapolis to Syracuse Bus

With Busbud, comparing and booking tickets for a bus from Indianapolis to Syracuse is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from Indianapolis to Syracuse.

Whether it is cheap bus tickets or more luxurious buses going to Syracuse from Indianapolis, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Indianapolis - Syracuse, US

  1. How far is Syracuse from Indianapolis by coach?

    The journey from Indianapolis to Syracuse by coach covers an approximate distance of 565 miles (912 km).

  2. What is the best way to go from Indianapolis to Syracuse without flying?

    To travel from Indianapolis to Syracuse without flying, you can take the coaches. The coach ensures a pleasant travel experience, granting you the opportunity to appreciate the scenery as you make your way to your final stop. You also have the option of utilising carpooling services.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
04/07
US$167
05/07
No data
Today
No data
07/07
US$198
08/07
No data
09/07
US$174
10/07
No data
11/07
No data
busbud logoThe cheapest trip from Indianapolis to Syracuse was searched and found on 4 Jul 2025 with a price of US$167

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Indianapolis to Syracuse as early as possible.

You can expect to pay from US$167 to US$1,810 for a bus ticket from Indianapolis to Syracuse based on the last 2 days. You can expect to find the cheapest price for the trip at US$174, which is on 2025-07-09.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Indianapolis to Syracuse.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Indianapolis to Syracuse.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Indianapolis to Syracuse.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Indianapolis to Syracuse.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

What's the cheapest way to go from Indianapolis to Syracuse?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Indianapolis by bus?

Bus from Indianapolis to Syracuse

You can also go to Syracuse by train

Train from Indianapolis to Syracuse

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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