What is the distance between Indianapolis and Syracuse?

Indianapolis and Syracuse are 565 miles (912 km) apart.

What are the departure and arrival stations when taking the bus from Indianapolis to Syracuse?

If you're headed to Syracuse from Indianapolis, chances are that your bus will depart from Greyhound Amtrak Station and arrive at Syracuse Airport. These are the most popular pick-up and drop-off locations on this route, but you can find others that could fit better into your travel plans.

What are the best sights and things to do in Syracuse?

Once in Syracuse, you can start exploring the city and discover its surroundings. The top sights and things to do are Webster Pond, The Fun Warehouse, Landmark Theatre, Oncenter War Memorial Arena and Erie Canal Museum.

Bus Indianapolis to Syracuse from $116 | Compare & Save up to 60%

TodayJun 23

from $224

TomorrowJun 24

from $136

WedJun 25

ThuJun 26

FriJun 27

from $122

SatJun 28

SunJun 29

MonJun 30

from $156

Next departures to Syracuse

One passenger / one way

This trip is recommended because it is: Cheapest
Departure time: June 24 at 3:15am
Departure city: Indianapolis
Departure location: Downtown Transit Center
Arrival time: June 25 at 1:40am
Destination city: Syracuse
Destination location: Syracuse (Regional Transportation Center)
Operated by: FlixBus + Greyhound Lines, Inc.
FlixBus + Greyhound Lines, Inc.
Vehicle: BusDuration: 22h 25m
This trip is recommended because it is: Fastest
Departure time: June 24 at 12:20am
Departure city: Indianapolis
Departure location: Downtown Transit Center
Arrival time: June 24 at 8:25pm
Destination city: Syracuse
Destination location: Syracuse (Regional Transportation Center)
Operated by: FlixBus + Greyhound Lines, Inc.
FlixBus + Greyhound Lines, Inc.
Vehicle: BusDuration: 20h 5m
Departure time: June 24 at 10:50am
Departure city: Indianapolis
Departure location: Greyhound Amtrak Station
Arrival time: June 25 at 3:45pm
Destination city: Syracuse
Destination location: SYR Airport
Operated by: Amtrak
Vehicle: BusDuration: 1d 4h
Departure time: June 24 at 8:10pm
Departure city: Indianapolis
Departure location: Indianapolis Bus Station
Arrival time: June 25 at 8:25pm
Destination city: Syracuse
Destination location: Syracuse (Regional Transportation Center)
Operated by: Greyhound Lines, Inc.
Vehicle: BusDuration: 1d
Departure time: June 24 at 12:20am
Departure city: Indianapolis
Departure location: Downtown Transit Center
Arrival time: June 24 at 8:25pm
Destination city: Syracuse
Destination location: Syracuse (Regional Transportation Center)
Operated by: FlixBus + Greyhound Lines, Inc.
FlixBus + Greyhound Lines, Inc.
Vehicle: BusDuration: 20h 5m

Accepted payments

Compare 2 ways to go from Indianapolis to Syracuse.

	Average Price	Average Duration	CO₂ emissions
Bus	Average Price$74 - $253	Average Duration22h 25m	CO₂ emissions 23kg CO₂e5 out of 5 stars	CheapestFastestMost eco-friendly
Train	Average Price$195 - $651	Average Duration1d 5h	CO₂ emissions 83kg CO₂e1 out of 5 stars

Busbud recommends taking the bus from Indianapolis to Syracuse

Among the sustainable travel choices, the bus stands out as the good way to reach Syracuse. The journey takes about 22 hours 25 minutes and with fares starting at just $74, it presents an excellent value for a comfortable ride.

6bus per day

22h 25mAverage Duration

$74Cheapest ticket

23kgCO₂ emissions

Bus Indianapolis to Syracuse: Trip Overview

Average ticket price$155

Average bus trip duration22h 25m

Number of daily buses5.611111111111111

Earliest bus departure12:20am

Distance564 miles (909 km)

Latest bus departure11:30pm

Compare bus companies

Greyhound

3.5/587,052 reviews

Staff3.6

Timeliness2.8

Cleanliness3.3

Wifi2.3

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

FlixBus

3.5/59,195 reviews

Staff4.1

Timeliness4

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

Amtrak

4/55,229 reviews

Staff4.7

Timeliness3.8

Cleanliness4.6

Wifi3.6

Greyhound US

US bus companies: FlixBus, Greyhound, Tornado Bus, Los Limousines, Valley Transit, Tufesa, New York Trailways

Indianapolis to Syracuse Bus

With Busbud, comparing and booking tickets for a bus from Indianapolis to Syracuse is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from Indianapolis to Syracuse.

Whether it is cheap bus tickets or more luxurious buses going to Syracuse from Indianapolis, we help you find what you're looking for based on how much of a budget you have.

Where are the popular stops in Indianapolis and Syracuse?

Stops in Indianapolis

A - Greyhound Amtrak Station

Stops in Syracuse

A - Syracuse Airport

B - Regional Transportation Center

C - Syracuse University

D - Syracuse University - Lyman Hall

E - New York State Fairgrounds

F - Syracuse, NY

Frequently asked questions for your trip Indianapolis - Syracuse, US

What is the distance between Indianapolis and Syracuse?
What are the departure and arrival stations when taking the bus from Indianapolis to Syracuse?
What are the best sights and things to do in Syracuse?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

06/21

$169

06/22

$143

Today

$217

06/24

$143

06/25

No data

06/26

No data

06/27

$131

06/28

No data

The cheapest trip from Indianapolis to Syracuse was searched and found on Jun 27, 2025 with a price of $131

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Indianapolis to Syracuse, as early as possible.

You can expect to pay from $131 to $1,585 for a bus ticket from Indianapolis to Syracuse based on the last 2 days. You can expect to find the cheapest price for the trip at $131 which is on 2025-06-27.

Usually Amtrak will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from Indianapolis to Syracuse.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Indianapolis to Syracuse.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Indianapolis to Syracuse.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Indianapolis to Syracuse.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

What's the cheapest way to go from Indianapolis to Syracuse?

The bus is the cheapest travel choice for this destination

Vehicle Type	Travel Time	Avg Price	Daily Departures
Vehicle TypeBus	Travel Time22h 25m	Avg Price$155	Daily Departures5.611111111111111
Vehicle TypeTrain	Travel Time1d 5h	Avg Price$220	Daily Departures1

Will you be returning to Indianapolis by bus?

Bus from Indianapolis to Syracuse

You can also go to Syracuse by train

Train from Indianapolis to Syracuse

Top traveled bus routes

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With several language and currency options available, Busbud seeks to cater to international bus travelers no matter where they are in the world. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

Bus Tickets from Indianapolis to Syracuse, US

One passenger / one way

Next departures to Syracuse

One passenger / one way

One passenger / one way

One passenger / one way

Compare 2 ways to go from Indianapolis to Syracuse.

Bus Indianapolis to Syracuse: Trip Overview

Compare bus companies

Indianapolis to Syracuse Bus

Where are the popular stops in Indianapolis and Syracuse?

Frequently asked questions for your trip Indianapolis - Syracuse, US

What is the distance between Indianapolis and Syracuse?

What are the departure and arrival stations when taking the bus from Indianapolis to Syracuse?

What are the best sights and things to do in Syracuse?

Find cheapest prices for buses

About Bus Travel

Bus Travel Tips

Did you know?

What's the cheapest way to go from Indianapolis to Syracuse?

Will you be returning to Indianapolis by bus?

You can also go to Syracuse by train

Top traveled bus routes

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

People from around the world trust Busbud

Popular Buses Connecting Indianapolis

Buses Leaving from Indianapolis

Buses Going to Indianapolis

Popular Buses Connecting Syracuse

Buses Leaving from Syracuse

Buses Going to Syracuse

Popular routes in this country

Popular airport transfers