Bus from Indianapolis to Syracuse, US: Tickets & Schedules

Previously seen trips

Next departures for Indianapolis to Syracuse on January 12
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound + FlixBus
Bus
Downtown Transit Center
Syracuse (Regional Transportation Center)No tags
Greyhound + FlixBus
Bus
Indianapolis Northeast
Syracuse (Regional Transportation Center)No tags
Greyhound + FlixBus
Bus
Indianapolis Bus Station
Syracuse (Regional Transportation Center)No tags
GreyhoundBus
Indianapolis Bus Station
Syracuse (Regional Transportation Center)No tags
Greyhound + FlixBus
Bus
Downtown Transit Center
Syracuse (Regional Transportation Center)No tags

Compare 2 ways to go from Indianapolis to Syracuse

We recommend taking the bus

Among the sustainable travel choices, the Bus stands out as the good way to reach Syracuse. The journey takes about 20 hours 55 minutes and with fares starting at just $95, it presents an excellent value for a comfortable ride.

3bus per day
20h 55mAverage Duration
564 milesDistance
23kgCO₂ emissions
Average Price$95 - $337Average Duration20h 55m
23kg CO₂e
Average Price$107 - $817Average Duration1d 5h
83kg CO₂e

Frequently asked questions about traveling from Indianapolis to Syracuse, US by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

  1. How much is the bus ticket from Indianapolis to Syracuse?

    The cheapest bus tickets from Indianapolis to Syracuse start from $95. The average price for this route is around $177. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the bus ride from Indianapolis to Syracuse?

    The average bus trip duration from Indianapolis to Syracuse is 20h 55m, covering a distance of 564 miles (910 km). The quickest bus can get you there in 20h 30m and is operated by FlixBus.

  3. Which bus companies service the Indianapolis to Syracuse route?

    Several major bus companies operate on this route with 3 buses available per day, including services from Amtrak, Greyhound, FlixBus.

  4. What is the earliest and latest departure time for the bus from Indianapolis to Syracuse?

    The earliest bus departs from Indianapolis to Syracuse at 12:15am. And the latest bus departs at 11:30pm.

  5. What are the CO₂ emissions for the bus trip from Indianapolis to Syracuse?

    A bus trip from Indianapolis to Syracuse generates an estimated 23 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

  6. What is the best bus company from Indianapolis to Syracuse?

    According to Busbud customers, the highest-rated bus company on this route is Amtrak, with an average rating of 4.1 out of 5 stars based on 5696 reviews.

  7. Which bus company has the best Wi-Fi from Indianapolis to Syracuse?

    Based on reviews on Busbud, the bus company Amtrak has the best Wi-Fi rating with a score of 3.6.

  8. Which bus company has the most timely service from Indianapolis to Syracuse?

    According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.

  9. Which bus company has the cleanest buses from Indianapolis to Syracuse?

    According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Amtrak, with a cleanliness rating of 4.5 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
01/10
No data
01/11
$150
Today
$123
01/13
No data
01/14
No data
01/15
No data
01/16
No data
01/17
No data
busbud logoThe cheapest trip from Indianapolis to Syracuse, US was searched and found on Jan 12, 2026 with a price of $123

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Indianapolis to Syracuse, US, as early as possible.

What's the cheapest way to go from Indianapolis to Syracuse, US?

busbud logoThe Bus is the cheapest travel choice for this destination

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