Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Bus | Jacksonville Bus Station | Downtown Transit Center | Cheapest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Jacksonville Bus Station | Indianapolis Bus Station | Fastest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Jacksonville Bus Station | Indianapolis Bus Station | No tags | ||||
 | Bus | Jacksonville Bus Station | Indianapolis Bus Station | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Jacksonville Bus Station | Indianapolis Bus Station | No tags |
Last refresh of the prices: Last Saturday at 9:56 AM EST.
Compare 2 ways to travel from Jacksonville to Indianapolis
Among the sustainable travel choices, the bus stands out as a good way to reach Indianapolis. The journey takes about 1 day and with fares starting at just R 2 310, it presents an excellent value for a comfortable ride.
Where are the popular stops in Jacksonville and Indianapolis?
Stops in Jacksonville
- A3570 Clifford Ln, Jacksonville, FL 32209, USA
- B
W Forsyth St
1111 W Forsyth St, Jacksonville, FL 32204, USA - C
Kings Avenue Station
1003 Kings Avenue, Jacksonville, FL 32207 - D
JRTC Greyhound Bus Station
111 W. Forsyth St, Jacksonville, FL 32202, USA
Compare bus companies
Frequently asked questions about travelling from Jacksonville, FL to Indianapolis by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Jacksonville to Indianapolis?
The cheapest bus tickets from Jacksonville to Indianapolis start at R 2 310. The average price for this route is around R 3 084. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Jacksonville to Indianapolis?
The average bus journey time from Jacksonville to Indianapolis is 1d , covering a distance of 1126 km. The fastest bus gets you there in 22h 25m and is operated by FlixBus.
Which bus companies service the Jacksonville to Indianapolis route?
What is the earliest and latest departure time for the bus from Jacksonville to Indianapolis?
The earliest bus departs from Jacksonville to Indianapolis at 09:05. And the latest bus departs at 22:05.
What are the CO₂ emissions for the bus trip from Jacksonville to Indianapolis?
A bus trip from Jacksonville to Indianapolis produces an estimated 28 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
What is the best bus company from Jacksonville to Indianapolis?
According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 11504 reviews.
Which bus company has the best Wi-Fi from Jacksonville to Indianapolis?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company offers the most punctual service from Jacksonville to Indianapolis?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Jacksonville to Indianapolis?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Jacksonville, FL to Indianapolis was searched and found on 15 Dec 2025 with a price of R 2 324To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Jacksonville, FL to Indianapolis as early as possible.
You can expect to pay from R 2 324 to R 3 495 for a bus ticket from Jacksonville, FL to Indianapolis based on the last 2 days. You can expect to find the cheapest price for the trip at R 2 599, which is on 2025-12-18.
What's the cheapest way to go from Jacksonville, FL to Indianapolis?
The bus is the cheapest travel choice for this destination
