Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Bus
| Jacksonville Bus Station | Indianapolis Bus Station | CheapestFastest | ||||
FlixBus + Greyhound Lines, Inc. | Bus
| Jacksonville Bus Station | Indianapolis Bus Station | No tags | ||||
 | Bus
| Jacksonville Bus Station | Indianapolis Bus Station | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus
| Jacksonville Bus Station | Indianapolis Bus Station | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus
| Jacksonville Bus Station | Indianapolis Bus Station | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus
| Jacksonville Bus Station | Indianapolis (W Vermont St) | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus
| Jacksonville Bus Station | Indianapolis (W Vermont St) | No tags |
Last refresh of the prices: Today at 5:10 PM EDT.
Compare 2 ways to travel from Jacksonville to Indianapolis
Among the sustainable travel choices, the Bus stands out as a good way to reach Indianapolis. The journey takes about 23 hours 30 minutes and with fares starting at just ARS 142 981, it presents an excellent value for a comfortable ride.
Bus stations and stops in Jacksonville and Indianapolis
Stops in Jacksonville
- A
Jacksonville Amtrak Station
3570 Clifford Ln, Jacksonville, FL 32209, USA - B
W Forsyth St
1111 W Forsyth St, Jacksonville, FL 32204, USA - C
Kings Avenue Station
1003 Kings Avenue, Jacksonville, FL 32207 - D
JRTC Greyhound Bus Station
111 W. Forsyth St, Jacksonville, FL 32202, USA
Compare bus companies
Frequently asked questions about travelling from Jacksonville, FL to Indianapolis by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Jacksonville to Indianapolis?
The cheapest bus tickets from Jacksonville to Indianapolis start at ARS 142 981. The average price for this route is around ARS 255 456. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Jacksonville to Indianapolis?
The average bus journey time from Jacksonville to Indianapolis is 23h 30m, covering a distance of 1132 km. The fastest bus gets you there in 20h 55m and is operated by Greyhound.
Which bus companies service the Jacksonville to Indianapolis route?
What is the earliest and latest departure time for the bus from Jacksonville to Indianapolis?
The earliest bus departs from Jacksonville to Indianapolis at 09:05. And the latest bus departs at 23:15.
What are the CO₂ emissions for the bus trip from Jacksonville to Indianapolis?
A bus trip from Jacksonville to Indianapolis produces an estimated 28.296100000000003 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
What is the best bus company from Jacksonville to Indianapolis?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 88108 reviews.
Which bus company has the best Wi-Fi from Jacksonville to Indianapolis?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company offers the most punctual service from Jacksonville to Indianapolis?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 4.0 out of 5 stars.
Which bus company has the cleanest buses from Jacksonville to Indianapolis?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Jacksonville, FL to Indianapolis was searched and found on 11 Sept 2026 with a price of ARS 158 233To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Jacksonville, FL to Indianapolis as early as possible.
You can expect to pay from ARS 158 233 to ARS 318 048 for a bus ticket from Jacksonville, FL to Indianapolis based on the last 2 days. You can expect to find the cheapest price for the trip at ARS 158 233, which is on 2026-09-11.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Jacksonville, FL to Indianapolis?
The Bus is the cheapest travel choice for this destination
