Bus Tickets from Jacksonville, FL to Indianapolis

Find affordable bus tickets from Jacksonville, FL to Indianapolis with flexible options. Book your trip now

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TodayJul 31
from US$230
TomorrowAug 1
from US$142
SatAug 2
from US$152
SunAug 3
from US$150
MonAug 4
from US$135
TueAug 5
WedAug 6
ThuAug 7

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: August 1 at
    Departure city: Jacksonville
    Departure location: Jacksonville Bus Station
    Arrival time: August 3 at
    Destination city: Indianapolis
    Destination location: Downtown Transit Center
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: August 1 at
    Departure city: Jacksonville
    Departure location: Jacksonville Bus Station
    Arrival time: August 2 at
    Destination city: Indianapolis
    Destination location: Indianapolis Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: August 1 at
    Departure city: Jacksonville
    Departure location: Jacksonville Bus Station
    Arrival time: August 2 at
    Destination city: Indianapolis
    Destination location: Indianapolis Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: August 1 at
    Departure city: Jacksonville
    Departure location: Jacksonville Bus Station
    Arrival time: August 2 at
    Destination city: Indianapolis
    Destination location: Indianapolis Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: August 1 at
    Departure city: Jacksonville
    Departure location: Jacksonville Bus Station
    Arrival time: August 2 at
    Destination city: Indianapolis
    Destination location: Downtown Transit Center
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:

Last refresh of the prices: Last Friday at 9:13 AM EDT.

Prices and availability are subject to change.

Accepted payments

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  • American Express
  • China Union Pay
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  • JCB payment
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Compare 2 ways to go from Jacksonville to Indianapolis

Bus
Average PriceUS$106 - US$274Average Duration23h 25m
28kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average PriceUS$275 - US$1,278Average Duration1d 12h
102kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Jacksonville to Indianapolis

Among the sustainable travel choices, the bus stands out as a good way to reach Indianapolis. The journey takes about 23 hours 25 minutes, and with fares starting at just US$106, it presents an excellent value for a comfortable ride.

8bus per day
23h 25mAverage Duration
US$106Cheapest ticket
28kgCO₂ emissions

Bus Jacksonville, FL to Indianapolis: Trip Overview

Average Ticket PriceUS$152
Average Bus Trip Duration23h 25m
Number of daily buses8
Earliest bus departure8:05am
Distance1125 km
Latest bus departure9:45pm

Jacksonville to Indianapolis Bus

Busbud helps you find a bus from Jacksonville to Indianapolis. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Jacksonville to Indianapolis from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses travelling from Jacksonville to Indianapolis, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Jacksonville, FL - Indianapolis

  1. What is the travel distance from Jacksonville to Indianapolis?

    The distance between Jacksonville and Indianapolis is approximately 1128 km (699 miles).

  2. What are the departure and arrival locations for buses traveling from Jacksonville to Indianapolis?

    Buses departing from Jacksonville Amtrak Station in Jacksonville will take you to Greyhound Amtrak Station in Indianapolis.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
07-29
US$102
07-30
No data
Today
US$217
08-01
US$134
08-02
US$151
08-03
US$142
08-04
US$130
08-05
No data
busbud logoThe cheapest trip from Jacksonville, FL to Indianapolis was searched and found on Jul 29, 2025 with a price of US$102

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Jacksonville, FL to Indianapolis, as early as possible.

You can expect to pay from US$102 to US$217 for a bus ticket from Jacksonville, FL to Indianapolis based on the last 2 days. You can expect to find the cheapest price for the trip at US$130 which is on 2025-08-04.

Usually Greyhound Lines, Inc. will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Jacksonville and Indianapolis!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Jacksonville to Indianapolis, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Jacksonville to Indianapolis that are otherwise impossible to come by with a plane.

Tune out to the fine sounds of your best music playlist on your bus trip from Jacksonville to Indianapolis while indulging in miles on end of beautiful scenic views.

Did you know?

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

What's the cheapest way to go from Jacksonville, FL to Indianapolis?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Jacksonville, FL by bus?

Bus from Jacksonville, FL to Indianapolis

You can also go to Indianapolis by train

Train from Jacksonville, FL to Indianapolis

Why choose Busbud?

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Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

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