Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Knoxville Bus Station | Roanoke Bus Stop | CheapestFastest |
Last refresh of the prices: Yesterday at 9:04 PM EST.
Get from Knoxville to Roanoke
The journey takes about 5 hours, and with fares starting at just R 882, it presents an excellent value for a comfortable ride.
Where are the popular stops in Knoxville and Roanoke?
Stops in Knoxville
- AKnoxville Area Transit Bus Stop, 100 Kirkwood St, Knoxville, TN 37914, USA
Stops in Roanoke
- AExit 140 (Park and Ride), Virginia 24153, USA
Compare bus companies
Based on 87434 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. Greyhound ticket prices on this trip start at R 882
Frequently asked questions about travelling from Knoxville, TN to Roanoke by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Knoxville to Roanoke?
The cheapest bus tickets from Knoxville to Roanoke start at R 882. The average price for this route is around R 1 002. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Knoxville to Roanoke?
The average bus journey time from Knoxville to Roanoke is 5h, covering a distance of 379 km. The fastest bus gets you there in 5h and is operated by Greyhound.
Which bus companies service the Knoxville to Roanoke route?
Several major bus companies operate on this route with 1 buses available per day.
What is the earliest and latest departure time for the bus from Knoxville to Roanoke?
The earliest bus departs from Knoxville to Roanoke at 22:50. And the latest bus departs at 22:50.
What are the CO₂ emissions for the bus trip from Knoxville to Roanoke?
A bus trip from Knoxville to Roanoke produces an estimated 9 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Knoxville, TN to Roanoke was searched and found on 15 Dec 2025 with a price of R 879To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Knoxville, TN to Roanoke as early as possible.
