Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Knoxville Bus Station | Roanoke Bus Stop | No tags | ||||
| Bus | Knoxville Bus Station | Roanoke Bus Stop | No tags | ||||
| Bus | Knoxville Bus Station | Roanoke Bus Stop | No tags | ||||
| Bus | Knoxville Bus Station | Roanoke Bus Stop | No tags | ||||
| Bus | Knoxville Bus Station | Roanoke Bus Stop | No tags |
Get from Knoxville to Roanoke
The journey takes about 5 hours, and with fares starting at just $73, it presents an excellent value for a comfortable ride.
Where are the popular stops in Knoxville and Roanoke?
Stops in Knoxville
- AKnoxville Area Transit Bus Stop, 100 Kirkwood St, Knoxville, TN 37914, USA
Stops in Roanoke
- AExit 140 (Park and Ride), Virginia 24153, USA
Compare bus companies
Based on 87433 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $73
Frequently asked questions about travelling from Knoxville, TN to Roanoke by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Knoxville to Roanoke?
The cheapest bus tickets from Knoxville to Roanoke start from $73. The average price for this route is around $80. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Knoxville to Roanoke?
The average bus travel time from Knoxville to Roanoke is 5h, covering a distance of 379 km. The quickest bus can get you there in 5h and is operated by Greyhound.
Which bus companies service the Knoxville to Roanoke route?
Several major bus companies operate on this route with 1 buses available per day.
What are the earliest and latest departure times for the bus from Knoxville to Roanoke?
The earliest bus departs from Knoxville to Roanoke at 10:50pm. And the latest bus departs at 10:50pm.
What are the CO₂ emissions for the bus trip from Knoxville to Roanoke?
A bus trip from Knoxville to Roanoke generates an estimated 9 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Knoxville, TN to Roanoke was searched and found on Dec 15, 2025 with a price of $72To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Knoxville, TN to Roanoke, as early as possible.
