Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | 1890 Avenida Sor Vicenta | Terminal Sur | Cheapest | |||||
| 1890 Avenida Sor Vicenta | Terminal Los Héroes | Fastest | |||||
 | Terminal de Buses de Los Angeles | Terminal Sur | No tags | |||||
| 1890 Avenida Sor Vicenta | Terminal Sur | No tags | |||||
 | 1890 Avenida Sor Vicenta | Terminal Sur | No tags |
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Get from Los Angeles to Santiago
This route is served by bus onlyThe journey takes about 5 hours 22 minutes, and with fares starting at just US$11, it presents an excellent value for a comfortable ride.
Bus Los Angeles, CL to Santiago, CL: Trip Overview
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Los Angeles to Santiago Bus
With Busbud, comparing and booking tickets for a bus from Los Angeles to Santiago is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
Bus service from Los Angeles to Santiago will be provided by the most trusted bus companies.
From cheap bus tickets to more luxurious buses travelling from Los Angeles to Santiago, we offer a wide range of bus services to best suit your needs depending on how much your budget is.
Where are the popular stops in Los Angeles and Santiago?
Frequently asked questions on the trip Los Angeles, CL - Santiago, CL
How much does a bus ticket from Los Angeles to Santiago cost?
The bus ticket price from Los Angeles to Santiago starts at US$11. The best way to find cheap bus tickets from Los Angeles to Santiago is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the bus ride from Los Angeles to Santiago?
The average travel time between Los Angeles and Santiago is around 5h 22m, although the fastest bus will take about 5h 19m. This is the time it takes to travel the 479 km that separates the two cities.
How many daily bus connections are there between Los Angeles and Santiago?
The number of buses from Los Angeles to Santiago can differ depending on the day of the week. On average, there are 39 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Los Angeles to Santiago by comparing and selecting the bus that fits your travel style and budget on Busbud.
Which bus companies travel from Los Angeles to Santiago?
When taking the bus from Los Angeles to Santiago, you can travel comfortably and safely with Eme Bus, buses TranSantin, Pullman Tur.
What are the departure and arrival stations when taking the bus from Los Angeles to Santiago?
Buses travelling between Los Angeles and Santiago leave from Terminal de Buses de Los Angeles or Terminal Tur Bus de Los Ángeles and arrive at Terminal Los Héroes, Terminal Sur, San Borja.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Los Angeles, CL to Santiago, CL was searched and found on 28 Oct 2025 with a price of US$12To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Los Angeles, CL to Santiago, CL as early as possible.
You can expect to pay from US$12 to US$41 for a bus ticket from Los Angeles, CL to Santiago, CL based on the last 2 days. You can expect to find the cheapest price for the trip at US$14, which is on 2025-11-01.
Usually buses TranSantin, Eme Bus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while travelling from Los Angeles to Santiago.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
Much more than a mere vehicle taking you from Los Angeles to Santiago, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.
Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Los Angeles to Santiago that are otherwise impossible to come by with a plane.
Make a music playlist for your bus ride from Los Angeles to Santiago, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.
The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!
Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!
Top travelled bus routes
Why choose Busbud?
The Best Way To Book Bus and Train Tickets
Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.
People from around the world trust Busbud
Popular Buses Connecting Los Angeles
Buses Leaving from Los Angeles
- Bus from Los Angeles to Victoria
- Coach Los Angeles - Chillan
- Bus Los Angeles - Talca
- Bus from Los Angeles to Valdivia
- Coach Los Angeles - Santiago
- Bus Los Angeles - Valparaiso
- Bus from Los Angeles to Concepción
- Coach Los Angeles - Osorno Province
- Bus Los Angeles - Castro
- Bus from Los Angeles to Nacimiento
- Coach Los Angeles - Puerto Montt
- Bus Los Angeles - Temuco
- Bus from Los Angeles to Talcahuano
- Coach Los Angeles - Puerto Varas
- Bus Los Angeles - Pucon
Buses Going to Los Angeles
- Bus from Santiago to Los Angeles
- Coach Concepción - Los Angeles
- Bus Puerto Montt - Los Angeles
- Bus from Pucon to Los Angeles
- Coach Valdivia - Los Angeles
- Bus Castro - Los Angeles
- Bus from Contulmo to Los Angeles
- Coach Ancud - Los Angeles
- Bus Angol - Los Angeles
- Bus from Vina del Mar to Los Angeles
- Coach Chillan - Los Angeles
- Bus Talcahuano - Los Angeles
- Bus from Victoria to Los Angeles
- Coach Osorno Province - Los Angeles
- Bus Renaico - Los Angeles
Popular Buses Connecting Santiago
Buses Leaving from Santiago
- Bus from Santiago to Puerto Montt
- Coach Santiago - Concepción
- Bus Santiago - Antofagasta
- Bus from Santiago to La Serena
- Coach Santiago - Temuco
- Bus Santiago - Mendoza
- Bus from Santiago to Vilcún
- Coach Santiago - Parral
- Bus Santiago - Labranza
- Bus from Santiago to Choshuenco
- Coach Santiago - Lanco
- Bus Santiago - Curacavi
- Bus from Santiago to Litueche
- Coach Santiago - Pinto
- Bus Santiago - Quirihue
Buses Going to Santiago
- Bus from Victoria to Santiago
- Coach Concepción - Santiago
- Bus Castro - Santiago
- Bus from Valdivia to Santiago
- Coach Mendoza - Santiago
- Bus Antofagasta - Santiago
- Bus from Lago Ranco to Santiago
- Coach Cholchol - Santiago
- Bus Chiguayante - Santiago
- Bus from Taltal to Santiago
- Coach Bulnes - Santiago
- Bus Parral - Santiago
- Bus from Teodoro Schmidt to Santiago
- Coach Melipeuco - Santiago
- Bus Talcahuano - Santiago