Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Melipeuco | Terminal Sur | CheapestFastest | ||||
 | Bus | Melipeuco | Terminal Sur | No tags | ||||
| Bus | Melipeuco | Terminal Sur | No tags | ||||
| Bus | Melipeuco | Terminal Sur | No tags |
Last refresh of the prices: Last Friday at 11:53 AM -03.
Get from Melipeuco to Santiago
The journey takes about 10 hours 10 minutes, and with fares starting at just R 309, it presents an excellent value for a comfortable ride.
Where are the popular stops in Melipeuco and Santiago?
Stops in Melipeuco
- A
Terminal Melipeuco
Pincheira, Melipeuco, IX Región, Chile
Stops in Santiago
- ASantiago - Av Libertador Bernardo O'Higgins 3850, Santiago, Estación Central, Región Metropolitana, Chile
- B
San Borja
San Francisco de Borja 199-225, Santiago, Estación Central, Región Metropolitana, Chile - CTucapel Jiménez 21, 8340528 Santiago, Región Metropolitana, Chile
- DPdte. Riesco 6391-6399, Las Condes, Región Metropolitana, Chile
- EAv. Gral. Oscar Bonilla 418, Lo Prado, Región Metropolitana, Chile
- F
Zapadores
Los Zapadores 608, Recoleta, Región Metropolitana, Chile
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Frequently asked questions about travelling from Melipeuco to Santiago, CL by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Melipeuco to Santiago?
The cheapest bus tickets from Melipeuco to Santiago start at R 309. The average price for this route is around R 404. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Melipeuco to Santiago?
The average bus journey time from Melipeuco to Santiago is 10h 10m, covering a distance of 607 km. The fastest bus gets you there in 10h and is operated by Nar Bus.
Which bus companies service the Melipeuco to Santiago route?
Several major bus companies operate on this route with 4 buses available per day, including services from Nar Bus, buses TranSantin.
What is the earliest and latest departure time for the bus from Melipeuco to Santiago?
The earliest bus departs from Melipeuco to Santiago at 20:00. And the latest bus departs at 20:40.
What are the CO₂ emissions for the bus trip from Melipeuco to Santiago?
A bus trip from Melipeuco to Santiago produces an estimated 15 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
What is the best bus company from Melipeuco to Santiago?
According to Busbud customers, the highest-rated bus company on this route is buses TranSantin, with an average rating of 4.2 out of 5 stars based on 284 reviews.
Which bus company has the best Wi-Fi from Melipeuco to Santiago?
Based on reviews on Busbud, the bus company Nar Bus has the best Wi-Fi rating with a score of 3.0.
Which bus company offers the most punctual service from Melipeuco to Santiago?
According to Busbud traveller reviews, the most punctual bus company on this route is buses TranSantin, with a punctuality rating of 4.3 out of 5 stars.
Which bus company has the cleanest buses from Melipeuco to Santiago?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is buses TranSantin, with a cleanliness rating of 4.5 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Melipeuco to Santiago, CL was searched and found on 17 Dec 2025 with a price of R 375To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Melipeuco to Santiago, CL as early as possible.
You can expect to pay from R 375 to R 454 for a bus ticket from Melipeuco to Santiago, CL based on the last 2 days. You can expect to find the cheapest price for the trip at R 375, which is on 2025-12-17.
Usually buses TranSantin will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
