Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Mesa Bus Stop | San Antonio Bus Station | CheapestFastest | ||||
Greyhound Lines, Inc. + Valley Transit | Bus | Mesa Bus Stop | San Antonio Bus Station | No tags | ||||
Greyhound Lines, Inc. + Greyhound Lines Mexico | Bus | Mesa Bus Stop | San Antonio Bus Station | No tags |
Last refresh of the prices: Today at 10:50 AM MST.
Get from Mesa to San Antonio
The journey takes about 1 day, 3 hours 15 minutes, and with fares starting at just R 2 102, it presents an excellent value for a comfortable ride.
Where are the popular stops in Mesa and San Antonio?
Stops in Mesa
- A
Mesa Bus Station
1423 S Country Club , Mesa, AZ 85210, USA
Stops in San Antonio
- A500 N St Mary's St, San Antonio, TX 78205, USA
- B7914 Interstate 35 Access Rd, San Antonio, TX 78224, USA
- C4407 S PanAm Expy #101, San Antonio, TX 78225, USA
- D165 Bowie St, San Antonio, 78205
Compare bus companies
Based on 87519 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained about the Wi-Fi. Greyhound ticket prices on this trip start at R 2 102
Frequently asked questions about travelling from Mesa to San Antonio, US by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Mesa to San Antonio?
The cheapest bus tickets from Mesa to San Antonio start at R 2 102. The average price for this route is around R 3 233. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Mesa to San Antonio?
The average bus journey time from Mesa to San Antonio is 1d 3h, covering a distance of 1340 km. The fastest bus gets you there in 19h 35m and is operated by Greyhound.
Which bus companies service the Mesa to San Antonio route?
Several major bus companies operate on this route with 2 buses available per day.
What is the earliest and latest departure time for the bus from Mesa to San Antonio?
The earliest bus departs from Mesa to San Antonio at 03:50. And the latest bus departs at 19:15.
What are the CO₂ emissions for the bus trip from Mesa to San Antonio?
A bus trip from Mesa to San Antonio produces an estimated 33 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Mesa to San Antonio, US was searched and found on 04 Feb 2026 with a price of R 2 722To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Mesa to San Antonio, US as early as possible.
You can expect to pay from R 2 722 to R 2 722 for a bus ticket from Mesa to San Antonio, US based on the last 2 days. You can expect to find the cheapest price for the trip at R 2 722, which is on 2026-02-04.
