- Mexico City to Panama City buses
Previously seen journeys
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound | Mexico City Buenavista (Forum) | Panama City Beach Station | No tags | |||||
Greyhound + FlixBus | Mexico City Buenavista (San Pedro Santa Clara) | Panama City Beach Station | No tags | |||||
FlixBus + Greyhound | Mexico City Buenavista (Forum) | Panama City Beach Station | No tags | |||||
FlixBus + Greyhound | Mexico City Buenavista (San Pedro Santa Clara) | Panama City Beach Station | No tags | |||||
FlixBus + Greyhound | Mexico City Buenavista (Forum) | Panama City Beach Station | No tags |
Accepted payments
Get from Mexico City to Panama City
The journey takes about 2 days, 7 hours 55 minutes, and with fares starting at just US$219, it presents an excellent value for a comfortable ride.
Bus Mexico City to Panama City, US: Trip Overview
Mexico City to Panama City Bus
Busbud helps you find a bus from Mexico City to Panama City. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
We make sure you can find a bus service from Mexico City to Panama City from the most reliable bus companies operating this trip.
Whether it is cheap bus tickets or more luxurious buses going to Panama City from Mexico City, we help you find what you're looking for based on how much of a budget you have.
Where are the popular stops in Mexico City and Panama City?
Frequently asked questions on the trip Mexico City - Panama City, US
How much does a bus ticket from Mexico City to Panama City cost?
The bus ticket price from Mexico City to Panama City starts at US$219. The best way to find cheap bus tickets from Mexico City to Panama City is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the bus ride from Mexico City to Panama City?
The average travel time between Mexico City and Panama City is around 2d 7h, although the fastest bus will take about 1d 20h. This is the time it takes to travel the 1808 km that separates the two cities.
How many daily bus connections are there between Mexico City and Panama City?
The number of buses from Mexico City to Panama City can differ depending on the day of the week. On average, there are 3 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Mexico City to Panama City by comparing and selecting the bus that fits your travel style and budget on Busbud.
What are the departure and arrival stations when taking the bus from Mexico City to Panama City?
Buses travelling between Mexico City and Panama City leave from Norte or TAPO and arrive at Panama City Greyhound Bus Station.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Mexico City and Panama City!
Start sightseeing the minute your bus leaves the station. If you're on the night bus from Mexico City to Panama City, get comfy and count the stars.
Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Mexico City to Panama City.
Tune out to the fine sounds of your best music playlist on your bus trip from Mexico City to Panama City while indulging in miles on end of beautiful scenic views.
Did you know?
Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.
Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!
The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!
Top travelled bus routes
Why choose Busbud?
The Best Way To Book Bus and Train Tickets
Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.
People from around the world trust Busbud
Popular Buses Connecting Mexico City
Buses Leaving from Mexico City
- Bus from Mexico City to Cancún
- Coach Mexico City - Centro
- Bus Mexico City - Denver
- Bus from Mexico City to Puebla
- Coach Mexico City - Tulum
- Bus Mexico City - Guanajuato
- Bus from Mexico City to Los Reyes
- Coach Mexico City - Sayula
- Bus Mexico City - Nuevo Casas Grandes
- Bus from Mexico City to Tenosique de Pino Suárez
- Coach Mexico City - Asuncion Ixtaltepec
- Bus Mexico City - Campeche
- Bus from Mexico City to Ciudad Mendoza
- Coach Mexico City - Barra de Navidad
- Bus Mexico City - Ruiz
Buses Going to Mexico City
- Bus from Chicago to Mexico City
- Coach Miami - Mexico City
- Bus Austin - Mexico City
- Bus from Temple to Mexico City
- Coach Dixon - Mexico City
- Bus Meridian - Mexico City
- Bus from Arriaga to Mexico City
- Coach San Pedro Tapanatepec - Mexico City
- Bus Chetumal - Mexico City
- Bus from Huamuxtitlán to Mexico City
- Coach Ayutla de los Libres - Mexico City
- Bus La Tinaja - Mexico City
- Bus from Tecozautla to Mexico City
- Coach Tepic - Mexico City
- Bus El Higo - Mexico City
Popular Buses Connecting Panama City
Buses Leaving from Panama City
- Bus from Panama City to Long Beach
- Coach Panama City - Miami
- Bus Panama City - San Jose
- Bus from Panama City to Atlanta
- Coach Panama City - Tallahassee
- Bus Panama City - Mexico City
- Bus from Panama City to Tulsa
- Coach Panama City - Chiefland
- Bus Panama City - Sarasota
- Bus from Panama City to Minneapolis
- Coach Panama City - Belle Glade
- Bus Panama City - Detroit
- Bus from Panama City to Madison
- Coach Panama City - Boston
- Bus Panama City - Beeville
Buses Going to Panama City
- Bus from Miami to Panama City
- Coach Atlanta - Panama City
- Bus Tallahassee - Panama City
- Bus from Tampa to Panama City
- Coach Chicago - Panama City
- Bus San Jose - Panama City
- Bus from Saint Paul to Panama City
- Coach San Francisco - Panama City
- Bus Waco - Panama City
- Bus from Raceland to Panama City
- Coach Yuma - Panama City
- Bus Evergreen - Panama City
- Bus from Murfreesboro to Panama City
- Coach Seattle - Panama City
- Bus Lake Charles - Panama City





