Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Bus Station | Indianapolis Bus Station | CheapestFastest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Bus Station | Downtown Transit Center | No tags |
Last refresh of the prices: Today at 10:25 AM EST.
Get from Myrtle Beach to Indianapolis
The journey takes about 22 hours 10 minutes, and with fares starting at just R 1 844, it presents an excellent value for a comfortable ride.
Where are the popular stops in Myrtle Beach and Indianapolis?
Compare bus companies
Based on 87520 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained about the Wi-Fi. Greyhound ticket prices on this trip start at R 1 844
Frequently asked questions about travelling from Myrtle Beach to Indianapolis by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Myrtle Beach to Indianapolis?
The cheapest bus tickets from Myrtle Beach to Indianapolis start at R 1 844. The average price for this route is around R 2 313. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Myrtle Beach to Indianapolis?
The average bus journey time from Myrtle Beach to Indianapolis is 22h 10m, covering a distance of 936 km. The fastest bus gets you there in 22h 10m and is operated by Greyhound.
Which bus companies service the Myrtle Beach to Indianapolis route?
Several major bus companies operate on this route with 1 buses available per day.
What is the earliest and latest departure time for the bus from Myrtle Beach to Indianapolis?
The earliest bus departs from Myrtle Beach to Indianapolis at 13:55. And the latest bus departs at 13:55.
What are the CO₂ emissions for the bus trip from Myrtle Beach to Indianapolis?
A bus trip from Myrtle Beach to Indianapolis produces an estimated 23 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Myrtle Beach to Indianapolis was searched and found on 09 Feb 2026 with a price of R 1 727To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Myrtle Beach to Indianapolis as early as possible.
You can expect to pay from R 1 727 to R 3 322 for a bus ticket from Myrtle Beach to Indianapolis based on the last 2 days. You can expect to find the cheapest price for the trip at R 1 727, which is on 2026-02-09.
