Bus Tickets from Myrtle Beach, SC to Indianapolis, IN

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Bus Myrtle Beach to Indianapolis: Trip Overview

Average ticket price$161
Average bus trip duration1d 8h
Number of daily buses2
Earliest bus departure12:45pm
Distance580 miles (935 km)

Myrtle Beach to Indianapolis Bus

With Busbud, comparing and booking tickets for a bus from Myrtle Beach to Indianapolis is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from Myrtle Beach to Indianapolis from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to Indianapolis from Myrtle Beach, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions for your trip Myrtle Beach - Indianapolis

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
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$144
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busbud logoThe cheapest trip from Myrtle Beach to Indianapolis was searched and found on May 6, 2025 with a price of $144

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Myrtle Beach to Indianapolis, as early as possible.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from Myrtle Beach to Indianapolis.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Myrtle Beach to Indianapolis, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Myrtle Beach to Indianapolis.

Tune out to the fine sounds of your best music playlist on your bus trip from Myrtle Beach to Indianapolis while indulging in miles on end of beautiful scenic views.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Will you be returning to Myrtle Beach by bus?

Bus from Myrtle Beach to Indianapolis

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