Find coaches from Panama City, US to Gainesville, FL

Previously seen journeys

Next departures from Panama City to Gainesville on 30 October
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound
Panama City Beach Station
Gainesville Bus StopNo tags
Greyhound
Panama City Beach Station
Gainesville Bus StopNo tags
Greyhound
Panama City Beach Station
Gainesville Bus StopNo tags
Greyhound
Panama City Beach Station
Gainesville Bus StopNo tags
Greyhound
Panama City Beach Station
Gainesville Bus StopNo tags

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Get from Panama City to Gainesville

busbud logoThis route is served by bus only

The journey takes about 10 hours 40 minutes, and with fares starting at just US$37, it presents an excellent value for a comfortable ride.

1bus per day
10h 40mAverage duration
334 kmDistance
8kgCO₂ emissions

Bus Panama City, US to Gainesville, FL: Trip Overview

Average ticket priceUS$47
Average bus trip duration10h 40m
Number of daily buses1
Earliest bus departure07:25
Distance333 km
Latest bus departure12:50

Panama City to Gainesville Bus

Busbud helps you find a bus from Panama City to Gainesville. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Panama City to Gainesville from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to Gainesville from Panama City, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Panama City, US - Gainesville, FL

  1. How much does a bus ticket from Panama City to Gainesville cost?

    The bus ticket price from Panama City to Gainesville starts at US$37. The best way to find cheap bus tickets from Panama City to Gainesville is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

  2. How long is the bus ride from Panama City to Gainesville?

    The average travel time between Panama City and Gainesville is around 10h 40m, although the fastest bus will take about 5h 35m. This is the time it takes to travel the 328 km that separates the two cities.

  3. How many daily bus connections are there between Panama City and Gainesville?

    The number of buses from Panama City to Gainesville can differ depending on the day of the week. On average, there are 1 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Panama City to Gainesville by comparing and selecting the bus that fits your travel style and budget on Busbud.

  4. Which bus companies travel from Panama City to Gainesville?

    When taking the bus from Panama City to Gainesville, you can travel comfortably and safely with Greyhound.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
28/10
US$39
29/10
No data
Today
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31/10
No data
01/11
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02/11
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03/11
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busbud logoThe cheapest trip from Panama City, US to Gainesville, FL was searched and found on 28 Oct 2025 with a price of US$39

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Panama City, US to Gainesville, FL as early as possible.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Panama City and Gainesville!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Panama City to Gainesville, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Panama City to Gainesville.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Panama City to Gainesville.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

Will you be returning to Panama City, US by bus?

Bus from Gainesville, FL to Panama City, US

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. Use Busbud to book your trip online, in your own language and currency, wherever you are. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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