Bus Tickets from Panama City, US to Gainesville (FL)

Find affordable bus tickets from Panama City, US to Gainesville (FL) with flexible options. Book your trip now

Join 75M+ travelers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every step.
Cancel anytime and receive a 100% refund, no reason needed.
TodayJun 15
TomorrowJun 16
TueJun 17
WedJun 18
from US$63
ThuJun 19
FriJun 20
from US$66
SatJun 21
from US$65
SunJun 22

Cheap buses leaving Wednesday

One passenger / one way

  • This trip is recommended because it is the: Cheapest + Fastest
    Departure time: June 18 at
    Departure city: Panama City
    Departure location: Panama City Beach Station
    Arrival time: June 19 at
    Destination city: Gainesville
    Destination location: Gainesville Bus Stop
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

Last refresh of the prices: Last Wednesday at 6:06 AM CDT.

Prices and availability are subject to change.

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Bus Panama City to Gainesville: Trip Overview

Average Ticket PriceUS$75
Average Bus Trip Duration10h 30m
Number of daily buses1
Earliest bus departure12:50pm
Distance333 km

Panama City to Gainesville Bus

Busbud helps you find a bus from Panama City to Gainesville. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Panama City to Gainesville from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to Gainesville from Panama City, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Panama City, US - Gainesville (FL)

  1. How long is the trip from Panama City to Gainesville by bus?

    The bus ride from Panama City to Gainesville takes 10h 30m, on average. The fastest bus on this trip will get to Gainesville in 10h 30m

  2. What is the travel distance from Panama City to Gainesville?

    Panama City and Gainesville are 328 km (204 miles) apart.

  3. What are the departure and arrival locations for buses traveling from Panama City to Gainesville?

    Buses departing from Panama City Greyhound Bus Station in Panama City will take you to Rosa Parks Station in Gainesville.

  4. What is the cheapest way to get from Panama City to Gainesville?

    Taking the bus is the most budget-friendly option to travel from Panama City to Gainesville. With a starting ticket price of US$75, this bus becomes your top pick for this journey.

  5. How much does the bus ticket cost from Panama City to Gainesville?

    The bus from Panama City to Gainesville will cost you US$75, on average.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
06-13
No data
06-14
US$67
Today
No data
06-16
No data
06-17
No data
06-18
US$55
06-19
No data
06-20
US$59
busbud logoThe cheapest trip from Panama City to Gainesville was searched and found on Jun 18, 2025 with a price of US$55

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Panama City to Gainesville, as early as possible.

You can expect to pay from US$55 to US$67 for a bus ticket from Panama City to Gainesville based on the last 2 days. You can expect to find the cheapest price for the trip at US$55 which is on 2025-06-18.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Panama City and Gainesville!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Panama City to Gainesville, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Panama City to Gainesville.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Panama City to Gainesville.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

Will you be returning to Panama City by bus?

Bus from Panama City to Gainesville

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. Use Busbud to book your trip online, in your own language and currency, wherever you are. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

People from around the world trust Busbud

‌

Popular Buses Connecting Panama City

Buses Leaving from Panama City

Buses Going to Panama City

Popular Buses Connecting Gainesville

Buses Leaving from Gainesville

Buses Going to Gainesville