Next bus departures

Next departures from Philadelphia to Florence on 29 July
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	18:30	Philadelphia Bus Station	11h 15m	05:45	Florence, SC	CheapestFastest
	Bus	20:05	Philadelphia Bus Station	15h 54m	11:59	Bus station	No tags
FlixBus + Greyhound Lines, Inc.	Bus	22:30	Philadelphia Bus Station	18h 25m	16:55	Bus station	No tags
	Bus	14:05	Camden (Walter Rand Transportation Center)	21h 54m	11:59	Bus station	No tags

Next departures from Philadelphia to Florence on 30 July
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	03:05	Philadelphia Bus Station	13h 50m	16:55	Bus station	Cheapest
	Bus	18:30	Philadelphia Bus Station	11h 15m	05:45	Florence, SC	Fastest
	Bus	00:05	Philadelphia Bus Station	11h 54m	11:59	Bus station	No tags
FlixBus + Greyhound Lines, Inc.	Bus	22:30	Philadelphia Bus Station	18h 25m	16:55	Bus station	No tags
	Bus	20:05	Philadelphia Bus Station	15h 54m	11:59	Bus station	No tags
	Bus	14:05	Camden (Walter Rand Transportation Center)	21h 54m	11:59	Bus station	No tags

Next departures from Philadelphia to Florence on 31 July
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	14:05	Camden (Walter Rand Transportation Center)	21h 54m	11:59	Bus station	Cheapest
	Bus	18:30	Philadelphia Bus Station	11h 15m	05:45	Florence, SC	Fastest
	Bus	00:05	Philadelphia Bus Station	11h 54m	11:59	Bus station	No tags
FlixBus + Greyhound Lines, Inc.	Bus	03:05	Philadelphia Bus Station	13h 50m	16:55	Bus station	No tags
FlixBus + Greyhound Lines, Inc.	Bus	22:00	Philadelphia Bus Station	13h 59m	11:59	Bus station	No tags
FlixBus + Greyhound Lines, Inc.	Bus	22:30	Philadelphia Bus Station	18h 25m	16:55	Bus station	No tags

Next departures from Philadelphia to Florence on 1 August
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	18:30	Philadelphia Bus Station	11h 15m	05:45	Florence, SC	CheapestFastest
	Bus	00:05	Philadelphia Bus Station	11h 54m	11:59	Bus station	No tags
FlixBus + Greyhound Lines, Inc.	Bus	03:05	Philadelphia Bus Station	13h 50m	16:55	Bus station	No tags
FlixBus + Greyhound Lines, Inc.	Bus	22:00	Philadelphia Bus Station	13h 59m	11:59	Bus station	No tags
	Bus	14:05	Camden (Walter Rand Transportation Center)	21h 54m	11:59	Bus station	No tags
FlixBus + Greyhound Lines, Inc.	Bus	22:30	Philadelphia Bus Station	18h 25m	16:55	Bus station	No tags

Next departures from Philadelphia to Florence on 3 August
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	14:05	Camden (Walter Rand Transportation Center)	21h 54m	11:59	Bus station	Cheapest
	Bus	00:05	Philadelphia Bus Station	11h 54m	11:59	Bus station	Fastest
FlixBus + Greyhound Lines, Inc.	Bus	03:05	Philadelphia Bus Station	13h 50m	16:55	Bus station	No tags
FlixBus + Greyhound Lines, Inc.	Bus	22:00	Philadelphia Bus Station	13h 59m	11:59	Bus station	No tags
FlixBus + Greyhound Lines, Inc.	Bus	22:30	Philadelphia Bus Station	18h 25m	16:55	Bus station	No tags

Next departures from Philadelphia to Florence on 5 August
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	18:30	Philadelphia Bus Station	11h 15m	05:45	Florence, SC	CheapestFastest
	Bus	00:05	Philadelphia Bus Station	11h 54m	11:59	Bus station	No tags
FlixBus + Greyhound Lines, Inc.	Bus	03:05	Philadelphia Bus Station	13h 50m	16:55	Bus station	No tags
	Bus	20:05	Philadelphia Bus Station	15h 54m	11:59	Bus station	No tags
FlixBus + Greyhound Lines, Inc.	Bus	22:30	Philadelphia Bus Station	18h 25m	16:55	Bus station	No tags
	Bus	14:05	Camden (Walter Rand Transportation Center)	21h 54m	11:59	Bus station	No tags

Last refresh of the prices: Yesterday at 6:36 PM EDT.

Compare 2 ways to travel from Philadelphia to Florence

We recommend taking the train

Among the sustainable travel choices, the Train stands out as a good way to reach Florence. The journey takes about 10 hours 55 minutes and with fares starting at just CLP 94 388, it presents an excellent value for a comfortable ride.

3train per day

10h 55mAverage duration

758 kmDistance

69kgCO₂ emissions

	Average price	Average duration	CO₂ emissions	Actions
Bus	Average priceCLP 75 837 - CLP 223 417	Average duration13h 59m	CO₂ emissions 19kg CO₂e
Train	Average priceCLP 94 388 - CLP 1 223 046	Average duration10h 55m	CO₂ emissions 69kg CO₂e

Bus stations and stops in Philadelphia and Florence

Stops in Philadelphia

A
Bus Station
1001 Filbert St, Philadelphia, PA 19107, USA
B
Philadelphia Airport
Visit page
C
#2842 St.Vincent St
15th St Trolley Station, Philadelphia, PA 19102, USA
D
Island Av & Suffolk Av MBFS
3000 Island Ave, Philadelphia, PA 19153, USA
E
Independence Travel Center
Off of Race Street between 5th Street and, N 6th St, Philadelphia, PA 19106, USA
Visit page
F
NRG SEPTA Station
3701 Broad St, Philadelphia, PA 19148, USA

Stops in Florence

A
Florence Bus Station
619 S Irby St, Florence, SC 29501, USA
Visit page
B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA

Compare bus companies

Greyhound

3.5/587 588 reviews

Staff3.6

Timeliness2.9

Cleanliness3.4

WiFi2.5

FlixBus

3.5/513 093 reviews

Staff4.2

Timeliness4.0

Cleanliness4.1

WiFi2.7

US bus companies:FlixBus, Greyhound, Futura, Elite, Chihuahuenses, Tufesa, Adirondack Trailways

Frequently asked questions about travelling from Philadelphia, PA, US to Florence, SC, US by bus

Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.

How much is the bus ticket from Philadelphia to Florence?
The cheapest bus tickets from Philadelphia to Florence start at CLP 75 837. The average price for this route is around CLP 96 439. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Philadelphia to Florence?
The average bus journey time from Philadelphia to Florence is 13h 59m, covering a distance of 761 km. The fastest bus gets you there in 11h 15m and is operated by FlixBus.
Which bus companies service the Philadelphia to Florence route?
Several major bus companies operate on this route with 5 buses available per day, including services from Greyhound, FlixBus.
What is the earliest and latest departure time for the bus from Philadelphia to Florence?
The earliest bus departs from Philadelphia to Florence at 00:05. And the latest bus departs at 22:30.
What are the CO₂ emissions for the bus trip from Philadelphia to Florence?
A bus trip from Philadelphia to Florence produces an estimated 19.002950000000002 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
What is the best bus company from Philadelphia to Florence?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87585 reviews.
Which bus company has the best Wi-Fi from Philadelphia to Florence?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company offers the most punctual service from Philadelphia to Florence?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 4.0 out of 5 stars.
Which bus company has the cleanest buses from Philadelphia to Florence?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

27/07

CLP 78 069

28/07

CLP 75 195

Today

CLP 177 248

30/07

CLP 207 922

31/07

CLP 145 147

01/08

CLP 112 097

02/08

CLP 113 534

03/08

CLP 127 419

The cheapest trip from Philadelphia, PA, US to Florence, SC, US was searched and found on 28 Jul 2026 with a price of CLP 75 195

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Philadelphia, PA, US to Florence, SC, US as early as possible.

You can expect to pay from CLP 75 195 to CLP 295 113 for a bus ticket from Philadelphia, PA, US to Florence, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at CLP 112 097, which is on 2026-08-01.

Usually Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.