Find coaches from Philadelphia, PA to Florence, SC, US

Find affordable coach tickets from Philadelphia, PA to Florence, SC, US with flexible options. Book your journey now

Join 75M+ travellers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every stage.
Cancel anytime and receive a 100% refund, no reason needed.
Today25 Jun
from US$116
Tomorrow26 Jun
from US$101
Fri27 Jun
from US$104
Sat28 Jun
from US$124
Sun29 Jun
from US$107
Mon30 Jun
from US$123
Tue1 Jul
from US$86
Wed2 Jul
from US$93

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: 26 June at
    Departure city: Philadelphia
    Departure location: 199 Spring Garden St.
    Arrival time: 27 June at
    Destination city: Florence
    Destination location: Bus station
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: 26 June at
    Departure city: Philadelphia
    Departure location: 199 Spring Garden St.
    Arrival time: 27 June at
    Destination city: Florence
    Destination location: Florence, SC
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: 26 June at
    Departure city: Philadelphia
    Departure location: 199 Spring Garden St.
    Arrival time: 27 June at
    Destination city: Florence
    Destination location: Florence, SC
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • Departure time: 26 June at
    Departure city: Philadelphia
    Departure location: Philadelphia, 199 Spring Garden St
    Arrival time: 27 June at
    Destination city: Florence
    Destination location: Florence, SC
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: 26 June at
    Departure city: Philadelphia
    Departure location: Philadelphia, 199 Spring Garden St
    Arrival time: 27 June at
    Destination city: Florence
    Destination location: Bus station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to travel from Philadelphia to Florence

Average priceUS$56 - US$252Average duration16h 15m
19kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Average priceUS$91 - US$312Average duration10h 50m
69kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the train from Philadelphia to Florence

Among the sustainable travel choices, the train stands out as a good way to reach Florence. The journey takes about 10 hours 50 minutes and with fares starting at just US$91, it presents an excellent value for a comfortable ride.

2train per day
10h 50mAverage duration
US$91Cheapest ticket
69kgCO₂ emissions

Bus Philadelphia to Florence: Trip Overview

Average ticket priceUS$107
Average bus trip duration16h 15m
Number of daily buses7.1034482758620685
Earliest bus departure07:05
Distance475 miles
Latest bus departure22:30

Philadelphia to Florence Bus

Busbud helps you find a bus from Philadelphia to Florence. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make it our job to connect you with the most dependable bus companies that cover bus service from Philadelphia to Florence.

Discover how much the bus trip from Philadelphia to Florence will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Philadelphia, PA - Florence, SC, US

  1. How far is Florence from Philadelphia by coach?

    The distance between Philadelphia and Florence by coach is approximately 467 miles (753 km).

  2. Is there a way to reach Florence from Philadelphia without flying?

    You have the option to select the coach for your journey on this route. The coach ensures a pleasant travel experience, granting you the opportunity to appreciate the scenery as you make your way to your final stop. You also have the option of utilising carpooling services.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
23/06
US$96
24/06
US$161
Today
US$149
26/06
US$118
27/06
US$136
28/06
US$134
29/06
US$122
30/06
US$120
busbud logoThe cheapest trip from Philadelphia to Florence was searched and found on 23 Jun 2025 with a price of US$96

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Philadelphia to Florence as early as possible.

You can expect to pay from US$96 to US$163 for a bus ticket from Philadelphia to Florence based on the last 2 days. You can expect to find the cheapest price for the trip at US$118, which is on 2025-06-26.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Philadelphia and Florence!

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Philadelphia to Florence.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Philadelphia to Florence will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Tune out to the fine sounds of your best music playlist on your bus trip from Philadelphia to Florence while indulging in miles on end of beautiful scenic views.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

What's the cheapest way to go from Philadelphia to Florence?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Philadelphia by bus?

Bus from Philadelphia to Florence

You can also go to Florence by train

Train from Philadelphia to Florence

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

People from around the world trust Busbud

Popular Buses Connecting Philadelphia

Buses Leaving from Philadelphia

Buses Going to Philadelphia

Popular Buses Connecting Florence

Buses Leaving from Florence

Buses Going to Florence