Bus from Philadelphia, PA to Florence, SC, US: Tickets & Schedules

Next bus departures

Next departures for Philadelphia to Florence on January 9
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus + Greyhound Lines, Inc.
Bus
Cherry Hill Mall
Bus stationCheapest
FlixBusBus
Philadelphia, 199 Spring Garden St
Florence, SCFastest
Greyhound Lines, Inc.Bus
199 Spring Garden St.
Bus stationNo tags
Greyhound Lines, Inc. + FlixBus
Bus
199 Spring Garden St.
Florence, SCNo tags
FlixBus + Greyhound Lines, Inc.
Bus
Philadelphia, 199 Spring Garden St
Bus stationNo tags

Last refresh of the prices: Yesterday at 7:56 AM EST.

Compare 2 ways to go from Philadelphia to Florence

We recommend taking the train

Among the sustainable travel choices, the Train stands out as a good way to reach Florence. The journey takes about 10 hours 55 minutes, and with fares starting at just $129, it presents an excellent value for a comfortable ride.

1train per day
10h 55mAverage Duration
758 kmDistance
69kgCO₂ emissions
Average Price$102 - $433Average Duration15h 45m
19kg CO₂e
Average Price$129 - $505Average Duration10h 55m
69kg CO₂e

Frequently asked questions about travelling from Philadelphia, PA to Florence, SC, US by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

  1. How much is the bus ticket from Philadelphia to Florence?

    The cheapest bus tickets from Philadelphia to Florence start from $102. The average price for this route is around $161. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the bus ride from Philadelphia to Florence?

    The average bus travel time from Philadelphia to Florence is 15h 45m, covering a distance of 762 km. The quickest bus can get you there in 11h 15m and is operated by FlixBus.

  3. Which bus companies service the Philadelphia to Florence route?

    Several major bus companies operate on this route with 8 buses available per day, including services from FlixBus, Greyhound.

  4. What are the earliest and latest departure times for the bus from Philadelphia to Florence?

    The earliest bus departs from Philadelphia to Florence at 7:10am. And the latest bus departs at 10:00pm.

  5. What are the CO₂ emissions for the bus trip from Philadelphia to Florence?

    A bus trip from Philadelphia to Florence generates an estimated 19 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.

  6. What is the best bus company from Philadelphia to Florence?

    According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 11828 reviews.

  7. Which bus company has the best Wi-Fi from Philadelphia to Florence?

    Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.

  8. Which bus company has the best on-time performance from Philadelphia to Florence?

    According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.

  9. Which bus company has the cleanest buses from Philadelphia to Florence?

    According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
01-07
$155
01-08
$160
Today
$163
01-10
No data
01-11
No data
01-12
No data
01-13
No data
01-14
No data
busbud logoThe cheapest trip from Philadelphia, PA to Florence, SC, US was searched and found on Jan 7, 2026 with a price of $155

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Philadelphia, PA to Florence, SC, US, as early as possible.

What's the cheapest way to go from Philadelphia, PA to Florence, SC, US?

busbud logoThe Bus is the cheapest travel choice for this destination

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