Bus Tickets from Philadelphia, PA to Florence, SC

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TodayMay 6
TomorrowMay 7
ThuMay 8
from US$144
FriMay 9
from US$86
SatMay 10
SunMay 11
from US$86
MonMay 12
TueMay 13

Cheap buses leaving Thursday

One passenger / one way

  • This trip is recommended because it is the: Cheapest + Fastest
    Departure time: May 8 at
    Departure city: Philadelphia
    Departure location: Philadelphia, 199 Spring Garden St
    Arrival time: May 9 at
    Destination city: Florence
    Destination location: Florence, SC
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: May 8 at
    Departure city: Philadelphia
    Departure location: Cherry Hill Mall
    Arrival time: May 9 at
    Destination city: Florence
    Destination location: Florence, SC
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: May 8 at
    Departure city: Philadelphia
    Departure location: Philadelphia (Logan Square)
    Arrival time: May 9 at
    Destination city: Florence
    Destination location: Florence, SC
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:

Last refresh of the prices: Last Thursday at 3:25 PM EDT.

Prices and availability are subject to change.

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to go from Philadelphia to Florence

Bus
Average PriceUS$61 - US$252Average Duration14h 50m
19kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average PriceUS$87 - US$386Average Duration10h 50m
69kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the train from Philadelphia to Florence

Among the sustainable travel choices, the train stands out as a good way to reach Florence. The journey takes about 10 hours 50 minutes, and with fares starting at just US$87, it presents an excellent value for a comfortable ride.

2train per day
10h 50mAverage Duration
US$87Cheapest ticket
69kgCO₂ emissions

Bus Philadelphia to Florence: Trip Overview

Average Ticket PriceUS$86
Average Bus Trip Duration14h 50m
Number of daily buses4
Earliest bus departure8:50am
Distance765 km
Latest bus departure8:00pm

Philadelphia to Florence Bus

Busbud helps you find a bus from Philadelphia to Florence. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make it our job to connect you with the most dependable bus companies that cover bus service from Philadelphia to Florence.

Discover how much the bus trip from Philadelphia to Florence will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Philadelphia - Florence

  1. How long is the trip from Philadelphia to Florence by bus?

    The typical travel time from Philadelphia to Florence by bus is around 14h 50m. If you're looking for the fastest way to get there, you'll find a bus doing the trip in about 11h 10m.

  2. What is the travel distance from Philadelphia to Florence?

    The distance between Philadelphia and Florence is around 753 km (467 miles).

  3. What are the departure and arrival locations for buses traveling from Philadelphia to Florence?

    Buses traveling this route start their trip at Philadelphia Airport, in Philadelphia, and end it at Florence Bus Station, in Florence.

  4. What is the cheapest way to go from Philadelphia to Florence?

    If you're on a budget, consider traveling by bus to Florence from Philadelphia; it tends to be more affordable. With a starting ticket price of US$61, this bus becomes your top pick for this journey.

  5. How much does the bus ticket cost from Philadelphia to Florence?

    The bus fare from Philadelphia to Florence is approximately US$86.

  6. Is there an overnight bus from Philadelphia to Florence?

    Yes! Catch buses leaving from Philadelphia until 8:00pm and reaching Florence on the following day.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05-04
US$133
05-05
No data
Today
No data
05-07
US$76
05-08
US$137
05-09
US$79
05-10
US$68
05-11
US$78
busbud logoThe cheapest trip from Philadelphia to Florence was searched and found on May 10, 2025 with a price of US$68

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Philadelphia to Florence, as early as possible.

You can expect to pay from US$68 to US$140 for a bus ticket from Philadelphia to Florence based on the last 2 days. You can expect to find the cheapest price for the trip at US$68 which is on 2025-05-10.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Philadelphia and Florence!

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Philadelphia to Florence.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Philadelphia to Florence will emit less CO2 than a car or an airplane.

Tune out to the fine sounds of your best music playlist on your bus trip from Philadelphia to Florence while indulging in miles on end of beautiful scenic views.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

What's the cheapest way to go from Philadelphia to Florence?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Philadelphia by bus?

Bus from Philadelphia to Florence

You can also go to Florence by train

Train from Philadelphia to Florence

Why choose Busbud?

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