Find coaches from Port Saint Lucie to Gainesville, FL

Previously seen journeys

Next departures from Port Saint Lucie to Gainesville on 31 October
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound + FlixBus
Port St Lucie (Park & Ride)
Gainesville Bus StopNo tags
Greyhound + FlixBus
Port St Lucie (Park & Ride)
Gainesville Bus StopNo tags
FlixBus
Port St Lucie (Park & Ride)
Rosa Parks StationNo tags
FlixBus + Greyhound
Port St Lucie (Park & Ride)
Gainesville Bus StopNo tags
FlixBus + Greyhound
Port St Lucie (Park & Ride)
Gainesville Bus StopNo tags

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Get from Port Saint Lucie to Gainesville

busbud logoThis route is served by bus only

The journey takes about 8 hours, and with fares starting at just US$36, it presents an excellent value for a comfortable ride.

4bus per day
8hAverage duration
332 kmDistance
8kgCO₂ emissions

Bus Port Saint Lucie to Gainesville, FL: Trip Overview

Average ticket priceUS$52
Average bus trip duration8h
Number of daily buses4
Earliest bus departure01:40
Distance332 km
Latest bus departure15:45

Port Saint Lucie to Gainesville Bus

Busbud helps you find a bus from Port Saint Lucie to Gainesville. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make it our job to connect you with the most dependable bus companies that cover bus service from Port Saint Lucie to Gainesville.

From cheap bus tickets to more luxurious buses travelling from Port Saint Lucie to Gainesville, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Port Saint Lucie - Gainesville, FL

  1. How much does a bus ticket from Port Saint Lucie to Gainesville cost?

    The bus ticket price from Port Saint Lucie to Gainesville starts at US$36. The best way to find cheap bus tickets from Port Saint Lucie to Gainesville is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

  2. How long is the bus ride from Port Saint Lucie to Gainesville?

    The average travel time between Port Saint Lucie and Gainesville is around 8h, although the fastest bus will take about 6h 10m. This is the time it takes to travel the 326 km that separates the two cities.

  3. How many daily bus connections are there between Port Saint Lucie and Gainesville?

    The number of buses from Port Saint Lucie to Gainesville can differ depending on the day of the week. On average, there are 4 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Port Saint Lucie to Gainesville by comparing and selecting the bus that fits your travel style and budget on Busbud.

  4. Which bus companies travel from Port Saint Lucie to Gainesville?

    When taking the bus from Port Saint Lucie to Gainesville, you can travel comfortably and safely with FlixBus, Greyhound.

  5. What are the departure and arrival stations when taking the bus from Port Saint Lucie to Gainesville?

    Buses travelling between Port Saint Lucie and Gainesville leave from Port St Lucie Mobil Gas Bus Stop or Port Saint Lucie - Wendys and arrive at Rosa Parks Station, Williston Rd & I-75, Greyhound Station.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
29/10
US$29
30/10
US$55
Today
US$53
01/11
No data
02/11
No data
03/11
No data
04/11
No data
05/11
No data
busbud logoThe cheapest trip from Port Saint Lucie to Gainesville, FL was searched and found on 29 Oct 2025 with a price of US$29

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Port Saint Lucie to Gainesville, FL as early as possible.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Port Saint Lucie and Gainesville!

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Port Saint Lucie to Gainesville.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Port Saint Lucie to Gainesville that are otherwise impossible to come by with a plane.

Make a music playlist for your bus ride from Port Saint Lucie to Gainesville, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

Will you be returning to Port Saint Lucie by bus?

Bus from Gainesville, FL to Port Saint Lucie

Why choose Busbud?

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