Find coaches from Portland, ME to St. Louis

Previously seen journeys

Next departures from Portland to St. Louis on 31 October
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound
    		Portland (Park & Ride)
    		Gateway StationNo tags
    Greyhound
      		Portland (Park & Ride)
      		Gateway StationNo tags
      Greyhound
        		Portland (Park & Ride)
        		Gateway StationNo tags
        Greyhound
          		Portland (Park & Ride)
          		Gateway StationNo tags
          Greyhound
            		Portland (Park & Ride)
            		Gateway StationNo tags

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            Compare 2 ways to travel from Portland to St. Louis

            We recommend taking the bus

            Among the sustainable travel choices, the bus stands out as a good way to reach St. Louis. The journey takes about 1 day, 10 hours 40 minutes and with fares starting at just US$265, it presents an excellent value for a comfortable ride.

            1bus per day
            1d 10hAverage duration
            1757 kmDistance
            44kgCO₂ emissions
            Bus
            		Average priceUS$265 - US$265Average duration1d 10h
            44kg CO₂e
            Train
            		Average priceUS$371 - US$371Average duration1d 14h
            160kg CO₂e

            Bus Portland, ME to St. Louis: Trip Overview

            Average ticket priceUS$265
            Average bus trip duration1d 10h
            Number of daily buses1
            Earliest bus departure13:45
            Distance1756 km

            Portland to St. Louis Bus

            With Busbud, comparing and booking tickets for a bus from Portland to St. Louis is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

            We make it our job to connect you with the most dependable bus companies that cover bus service from Portland to St. Louis.

            From cheap bus tickets to more luxurious buses travelling from Portland to St. Louis, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

            Frequently asked questions on the trip Portland, ME - St. Louis

            1. How much does a bus ticket from Portland to St. Louis cost?

              The bus ticket price from Portland to St. Louis starts at US$265. The best way to find cheap bus tickets from Portland to St. Louis is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

            2. How long is the bus ride from Portland to St. Louis?

              The average travel time between Portland and St. Louis is around 1d 10h, although the fastest bus will take about 1d 10h. This is the time it takes to travel the 1758 km that separates the two cities.

            3. How many daily bus connections are there between Portland and St. Louis?

              The number of buses from Portland to St. Louis can differ depending on the day of the week. On average, there are 1 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Portland to St. Louis by comparing and selecting the bus that fits your travel style and budget on Busbud.

            4. Which bus companies travel from Portland to St. Louis?

              When taking the bus from Portland to St. Louis, you can travel comfortably and safely with Greyhound, Amtrak.

            Find cheapest prices for buses

            Price is for a one-way ticket for one passenger and based on past searches.

            Best price found
            29/10
            No data
            30/10
            US$257
            Today
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            busbud logoThe cheapest trip from Portland, ME to St. Louis was searched and found on 30 Oct 2025 with a price of US$257

            To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Portland, ME to St. Louis as early as possible.

            About Bus Travel

            Bus Travel Tips

            Meet and talk to locals at the bus stations while travelling from Portland to St. Louis.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

            From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Portland to St. Louis.

            Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Portland to St. Louis that are otherwise impossible to come by with a plane.

            Tune out to the fine sounds of your best music playlist on your bus trip from Portland to St. Louis while indulging in miles on end of beautiful scenic views.

            Did you know?

            One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

            Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

            The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

            What's the cheapest way to go from Portland, ME to St. Louis?

            busbud logoThe bus is the cheapest travel choice for this destination

            Will you be returning to Portland, ME by bus?

            Bus from St. Louis to Portland, ME

            You can also go to St. Louis by train

            Train from Portland, ME to St. Louis

            Why choose Busbud?

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            Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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            Popular Buses Connecting Portland

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            Popular Buses Connecting St. Louis

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