Bus Tickets from Portland, ME to St. Louis

Find affordable bus tickets from Portland, ME to St. Louis with flexible options. Book your trip now

Join 75M+ travelers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every step.
Cancel anytime and receive a 100% refund, no reason needed.

Previously seen trips

One passenger / one way

  • Departure time: November 12 at
    Departure city: Portland
    Departure location: Portland (Park & Ride)
    Arrival time: November 13 at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:
  • Departure time: January 2 at
    Departure city: Portland
    Departure location: Portland (Park & Ride)
    Arrival time: January 3 at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:
  • Departure time: January 11 at
    Departure city: Portland
    Departure location: Portland (Park & Ride)
    Arrival time: January 12 at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:
  • Departure time: February 20 at
    Departure city: Portland
    Departure location: Portland (Park & Ride)
    Arrival time: February 21 at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:
  • Departure time: March 16 at
    Departure city: Portland
    Departure location: Portland (Park & Ride)
    Arrival time: March 17 at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to go from Portland to St. Louis

Bus
Average PriceUS$185 - US$185Average Duration1d 10h
44kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average PriceUS$189 - US$197Average Duration1d 14h
160kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Portland to St. Louis

Among the sustainable travel choices, the bus stands out as a good way to reach St. Louis. The journey takes about 1 day, 10 hours 50 minutes, and with fares starting at just US$185, it presents an excellent value for a comfortable ride.

1bus per day
1d 10hAverage Duration
US$185Cheapest ticket
44kgCO₂ emissions

Bus Portland, ME to St. Louis: Trip Overview

Average Ticket PriceUS$185
Average Bus Trip Duration1d 10h
Number of daily buses1
Earliest bus departure1:45pm
Distance1756 km

Portland to St. Louis Bus

With Busbud, comparing and booking tickets for a bus from Portland to St. Louis is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from Portland to St. Louis.

From cheap bus tickets to more luxurious buses travelling from Portland to St. Louis, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Portland, ME - St. Louis

  1. How far is Portland from St. Louis?

    Portland and St. Louis are 1758 km (1090 miles) apart.

  2. What are the departure and arrival locations for buses traveling from Portland to St. Louis?

    Buses departing from Greyhound Station Portland Maine in Portland will take you to Gateway Station in St. Louis.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Portland to St. Louis.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Portland to St. Louis.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Portland to St. Louis that are otherwise impossible to come by with a plane.

Tune out to the fine sounds of your best music playlist on your bus trip from Portland to St. Louis while indulging in miles on end of beautiful scenic views.

Did you know?

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

What's the cheapest way to go from Portland, ME to St. Louis?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Portland, ME by bus?

Bus from St. Louis to Portland, ME

You can also go to St. Louis by train

Train from Portland, ME to St. Louis

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

People from around the world trust Busbud

‌

Popular Buses Connecting Portland

Buses Leaving from Portland

Buses Going to Portland

Popular Buses Connecting St. Louis

Buses Leaving from St. Louis

Buses Going to St. Louis