Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | PRG Airport | Südseite Hauptbahnhof | CheapestFastest | ||||
| Bus | Prague (Central Bus Station Florenc) | Südseite Hauptbahnhof | No tags | ||||
| Bus | Prague (Central Bus Station Florenc) | Südseite Hauptbahnhof | No tags | ||||
| Bus | Prague (Central Bus Station Florenc) | Südseite Hauptbahnhof | No tags | ||||
| Bus | Prague (Central Bus Station Florenc) | Südseite Hauptbahnhof | No tags |
Last refresh of the prices: Today at 12:05 PM CET.
Compare 3 ways to travel from Prague to Karlsruhe
Among the sustainable travel choices, the Carpool stands out as a good way to reach Karlsruhe. The journey takes about 5 hours 20 minutes and with fares starting at just R 561, it presents an excellent value for a comfortable ride.
Where are the popular stops in Prague and Karlsruhe?
Stops in Prague
- AChlumecká, 198 00 Praha 20, Czech Republic
- BKřižíkova 2b, Nové Město, 186 00 Praha-Praha 8, Czech Republic
- C
Zličín
Drahoňovského, 163 00 Praha 17, Czech Republic - DAviatická, 161 08, Praha 6, Czechia
- ETomíčkova 2234, Chodov, 148 00 Praha-Praha 11, Czechia
- F300/8 Wilsonova, 110 00 Praha, Czechia
Stops in Karlsruhe
- AHinterm Hauptbahnhof 6, 76137 Karlsruhe, Germany
- BBahnhofpl. 1A, 76137 Karlsruhe, Germany
- CGoethestraße 17-19, 76135 Karlsruhe, Germany
- D
Karlsruhe
Gartenstraße 58, 76135 Karlsruhe, Germany - E
Karlsruhe/Baden-Baden Airport
Quebec Avenue, 77836 Rheinmünster, Germany
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Frequently asked questions about travelling from Prague to Karlsruhe by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Prague to Karlsruhe?
The cheapest bus tickets from Prague to Karlsruhe start at R 500. The average price for this route is around R 890. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Prague to Karlsruhe?
The average bus journey time from Prague to Karlsruhe is 10h 25m, covering a distance of 441 km. The fastest bus gets you there in 7h 50m and is operated by FlixBus.
Which bus companies service the Prague to Karlsruhe route?
Several major bus companies operate on this route with 12 buses available per day, including services from FlixBus, BlaBlaCar Bus, LEX CLUB.
What is the earliest and latest departure time for the bus from Prague to Karlsruhe?
The earliest bus departs from Prague to Karlsruhe at 02:30. And the latest bus departs at 23:50.
What are the CO₂ emissions for the bus trip from Prague to Karlsruhe?
A bus trip from Prague to Karlsruhe produces an estimated 11 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
What is the best bus company from Prague to Karlsruhe?
According to Busbud customers, the highest-rated bus company on this route is BlaBlaCar Bus, with an average rating of 3.7 out of 5 stars based on 11385 reviews.
Which bus company has the best Wi-Fi from Prague to Karlsruhe?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company offers the most punctual service from Prague to Karlsruhe?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Prague to Karlsruhe?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is BlaBlaCar Bus, with a cleanliness rating of 4.3 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Prague to Karlsruhe was searched and found on 26 Jan 2026 with a price of R 639To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Prague to Karlsruhe as early as possible.
You can expect to pay from R 639 to R 991 for a bus ticket from Prague to Karlsruhe based on the last 2 days. You can expect to find the cheapest price for the trip at R 639, which is on 2026-01-26.
