Next departures for Prague to Karlsruhe on November 19
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
PRG Airport
Südseite Hauptbahnhof
CheapestFastest
Prague (Central Bus Station Florenc)
Südseite Hauptbahnhof
No tags
Prague (Central Bus Station Florenc)
Südseite Hauptbahnhof
No tags
Prague (Central Bus Station Florenc)
Südseite Hauptbahnhof
No tags
Prague (Main Station - parking)
Südseite Hauptbahnhof
No tags
Next departures for Prague to Karlsruhe on November 20
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
PRG Airport
Südseite Hauptbahnhof
CheapestFastest
Prague (Central Bus Station Florenc)
Südseite Hauptbahnhof
No tags
Flixbus + Flixtrain
Prague (Central Bus Station Florenc)
Karlsruhe Hbf
No tags
Prague (Central Bus Station Florenc)
Südseite Hauptbahnhof
No tags
Flixbus + Flixtrain
Prague (Central Bus Station Florenc)
Karlsruhe Hbf
No tags
Last refresh of the prices: Yesterday at 9:31 AM CET.
Compare 3 ways to go from Prague to Karlsruhe
We recommend carpooling
Among the sustainable travel choices, the carpool stands out as the good way to reach Karlsruhe. The journey takes about 5 hours and with fares starting at just $25, it presents an excellent value for a comfortable ride.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Based on 11139 reviews, the company was rated 3.7 stars on Busbud. Travelers were especially satisfied with the ticket access and the staff but often complained with the wifi. BlaBlaCar Bus ticket prices on this trip start at $39
LEX CLUB offers 1 daily buses from Prague to Karlsruhe. Though the average price for this trip is $33, you can find tickets starting at $33. The trip between the two cities usually takes about 600.
Frequently asked questions about traveling from Prague to Karlsruhe by bus
What is the distance between Prague and Karlsruhe?
The distance separating Prague and Karlsruhe is 281 miles (453 km).
What are the departure and arrival stations when taking the bus from Prague to Karlsruhe?
If you're headed to Karlsruhe from Prague, chances are that your bus will leave from Zličín and arrive at Südseite Hauptbahnhof. These are the main departure and arrival locations on this route, but you could find others that could be a better fit for your travel plans.
What are the best sights and things to do in Karlsruhe?
Once in Karlsruhe, you can start exploring the city and discover its surroundings. The top sights and things to do are La Casserole (Baden-Baden), Hoepfner Burghof (Karlsruhe), Leo's Baden-Baden, Rive Gauche Brasserie (Baden-Baden) and Schwarzwaldstube (Karlsruhe).
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/17
$34
11/18
No data
Today
$33
11/20
$33
11/21
No data
11/22
No data
11/23
No data
11/24
No data
The cheapest trip from Prague to Karlsruhe was searched and found on Nov 20, 2025 with a price of $33
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Prague to Karlsruhe, as early as possible.
You can expect to pay from $33 to $65 for a bus ticket from Prague to Karlsruhe based on the last 2 days. You can expect to find the cheapest price for the trip at $33 which is on 2025-11-20.
The cheapest trip from Prague to Karlsruhe was searched and found on Nov 20, 2025 with a price of $33
