Find coaches from Roanoke to Knoxville, TN

Previously seen journeys

Next departures from Roanoke to Knoxville on 11 November
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
GreyhoundBus
Roanoke Bus Stop
Knoxville Bus StationNo tags
GreyhoundBus
Roanoke Bus Stop
Knoxville Bus StationNo tags
GreyhoundBus
Roanoke Bus Stop
Knoxville Bus StationNo tags
GreyhoundBus
Roanoke Bus Stop
Knoxville Bus StationNo tags
GreyhoundBus
Roanoke Bus Stop
Knoxville Bus StationNo tags

Get from Roanoke to Knoxville

This route is served by bus only

The journey takes about 5 hours 10 minutes, and with fares starting at just R 760, it presents an excellent value for a comfortable ride.

1bus per day
5h 10mAverage duration
379 kmDistance
9kgCO₂ emissions

Frequently asked questions about travelling from Roanoke to Knoxville, TN by bus

  1. How much does a bus ticket from Roanoke to Knoxville cost?

    The bus ticket price from Roanoke to Knoxville starts at R 760. The best way to find cheap bus tickets from Roanoke to Knoxville is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

  2. How long is the bus ride from Roanoke to Knoxville?

    The average travel time between Roanoke and Knoxville is around 5h 10m, although the fastest bus will take about 5h 10m. This is the time it takes to travel the 385 km that separates the two cities.

  3. How many daily bus connections are there between Roanoke and Knoxville?

    The number of buses from Roanoke to Knoxville can differ depending on the day of the week. On average, there are 1 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Roanoke to Knoxville by comparing and selecting the bus that fits your travel style and budget on Busbud.

  4. Which bus companies travel from Roanoke to Knoxville?

    When taking the bus from Roanoke to Knoxville, you can travel comfortably and safely with Greyhound.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
09/11
R 774
10/11
R 722
Today
No data
12/11
No data
13/11
No data
14/11
No data
15/11
No data
16/11
No data
busbud logoThe cheapest trip from Roanoke to Knoxville, TN was searched and found on 10 Nov 2025 with a price of R 722

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Roanoke to Knoxville, TN as early as possible.

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