Find coaches from Santa Ana, US to San Ysidro, CA

Next departures

Next departures from Santa Ana to San Ysidro on 31 October
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus
Santa Ana Bus Station
San Ysidro Bus terminalCheapest
Los Limousines
Santa Ana E Santa Ana Blvd
San Ysidro Greyhound Bus StationFastest
Greyhound Lines, Inc.
Anaheim Regional Transportation Intermodal Center
San Ysidro Bus terminalNo tags
FlixBus
Anaheim Regional Transportation Intermodal Center
San Ysidro Bus terminalNo tags
Los Limousines
Santa Ana E Santa Ana Blvd
San Ysidro Greyhound Bus StationNo tags

Last refresh of the prices: Today at 9:39 AM PDT.

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Get from Santa Ana to San Ysidro

busbud logoThis route is served by bus only

The journey takes about 3 hours, and with fares starting at just US$24, it presents an excellent value for a comfortable ride.

22bus per day
3hAverage duration
155 kmDistance
4kgCO₂ emissions

Bus Santa Ana, US to San Ysidro, CA: Trip Overview

Average ticket priceUS$45
Average bus trip duration3h
Number of daily buses22
Earliest bus departure05:55
Distance155 km
Latest bus departure22:45

Santa Ana to San Ysidro Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Santa Ana to San Ysidro.

We make sure you can find a bus service from Santa Ana to San Ysidro from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses travelling from Santa Ana to San Ysidro, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Santa Ana, US - San Ysidro, CA

  1. How much does a bus ticket from Santa Ana to San Ysidro cost?

    The bus ticket price from Santa Ana to San Ysidro starts at US$24. The best way to find cheap bus tickets from Santa Ana to San Ysidro is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

  2. How long is the bus ride from Santa Ana to San Ysidro?

    The average travel time between Santa Ana and San Ysidro is around 3h, although the fastest bus will take about 1h 45m. This is the time it takes to travel the 154 km that separates the two cities.

  3. How many daily bus connections are there between Santa Ana and San Ysidro?

    The number of buses from Santa Ana to San Ysidro can differ depending on the day of the week. On average, there are 22 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Santa Ana to San Ysidro by comparing and selecting the bus that fits your travel style and budget on Busbud.

  4. Which bus companies travel from Santa Ana to San Ysidro?

    When taking the bus from Santa Ana to San Ysidro, you can travel comfortably and safely with Los Limousines, FlixBus, Greyhound.

  5. What are the departure and arrival stations when taking the bus from Santa Ana to San Ysidro?

    Buses travelling between Santa Ana and San Ysidro leave from Santa Ana Greyhound Bus Station or 602 S Main St and arrive at San Ysidro Greyhound Bus Station.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
28/10
US$19
29/10
US$17
Today
US$19
31/10
US$19
01/11
US$18
02/11
US$23
03/11
US$17
04/11
US$17
busbud logoThe cheapest trip from Santa Ana, US to San Ysidro, CA was searched and found on 04 Nov 2025 with a price of US$17

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santa Ana, US to San Ysidro, CA as early as possible.

You can expect to pay from US$17 to US$49 for a bus ticket from Santa Ana, US to San Ysidro, CA based on the last 2 days. You can expect to find the cheapest price for the trip at US$17, which is on 2025-11-04.

Usually Los Limousines, Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Santa Ana to San Ysidro but it'll also be endearing to native speakers who will surely appreciate your effort.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Santa Ana to San Ysidro, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Santa Ana to San Ysidro that are otherwise impossible to come by with a plane.

Tune out to the fine sounds of your best music playlist on your bus trip from Santa Ana to San Ysidro while indulging in miles on end of beautiful scenic views.

Did you know?

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Will you be returning to Santa Ana, US by bus?

Bus from San Ysidro, CA to Santa Ana, US

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

People from around the world trust Busbud

‌

Popular Buses Connecting Santa Ana

Buses Leaving from Santa Ana

Buses Going to Santa Ana

Popular Buses Connecting San Ysidro

Buses Leaving from San Ysidro

Buses Going to San Ysidro