Bus from Santander to Madrid: Tickets & Timetables

Next bus departures

Next departures from Santander to Madrid on 15 December
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
ALSABus
    		Santander (Estacion de Autobuses)
    		MoncloaCheapest
    ALSA SupraBus
      		Santander (Estacion de Autobuses)
      		Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4Fastest
      ALSA SupraBus
        		Santander (Estacion de Autobuses)
        		Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4No tags
        FlixbusBus
        		Santander (Estacion de Autobuses)
        		Madrid (South)No tags
        ALSA SupraBus
          		Santander (Estacion de Autobuses)
          		Avenida de América MetroNo tags

          Last refresh of the prices: Yesterday at 10:38 PM CET.

          Compare 3 ways to travel from Santander to Madrid

          We recommend carpooling

          Among the sustainable travel choices, the carpool stands out as a good way to reach Madrid. The journey takes about 4 hours 20 minutes and with fares starting at just R 341, it presents an excellent value for a comfortable ride.

          17carpool per day
          4h 20mAverage duration
          339 kmDistance
          14kgCO₂ emissions
          Bus
          		Average priceR 742 - R 3 085Average duration5h 40m
          8kg CO₂e
          Train
          		Average priceR 562 - R 2 021Average duration4h 16m
          8kg CO₂e
          Carpool
          		Average priceR 341 - R 943Average duration4h 20m
          14kg CO₂e

          Frequently asked questions about travelling from Santander to Madrid by bus

          Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.

          1. How much is the bus ticket from Santander to Madrid?

            The cheapest bus tickets from Santander to Madrid start at R 742. The average price for this route is around R 922. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.

          2. How long is the bus journey from Santander to Madrid?

            The average bus journey time from Santander to Madrid is 5h 40m, covering a distance of 331 km. The fastest bus gets you there in 4h 25m and is operated by ALSA.

          3. Which bus companies service the Santander to Madrid route?

            Several major bus companies operate on this route with 14 buses available per day, including services from ALSA, FlixBus.

          4. What is the earliest and latest departure time for the bus from Santander to Madrid?

            The earliest bus departs from Santander to Madrid at 00:45. And the latest bus departs at 18:55.

          5. What are the CO₂ emissions for the bus trip from Santander to Madrid?

            A bus trip from Santander to Madrid produces an estimated 8 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.

          6. What is the best bus company from Santander to Madrid?

            According to Busbud customers, the highest-rated bus company on this route is ALSA, with an average rating of 4.3 out of 5 stars based on 60868 reviews.

          7. Which bus company has the best Wi-Fi from Santander to Madrid?

            Based on reviews on Busbud, the bus company ALSA has the best Wi-Fi rating with a score of 3.5.

          8. Which bus company offers the most punctual service from Santander to Madrid?

            According to Busbud traveller reviews, the most punctual bus company on this route is ALSA, with a punctuality rating of 4.3 out of 5 stars.

          9. Which bus company has the cleanest buses from Santander to Madrid?

            According to Busbud traveller reviews, the bus company with the cleanest buses on this route is ALSA, with a cleanliness rating of 4.7 out of 5 stars.

          Find cheapest prices for buses

          Price is for a one-way ticket for one passenger and based on past searches.

          Best price found
          13/12
          R 1 477
          14/12
          R 1 668
          Today
          R 743
          16/12
          R 684
          17/12
          R 687
          18/12
          R 684
          19/12
          R 739
          20/12
          R 743
          busbud logoThe cheapest trip from Santander to Madrid was searched and found on 16 Dec 2025 with a price of R 684

          To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santander to Madrid as early as possible.

          You can expect to pay from R 684 to R 2 227 for a bus ticket from Santander to Madrid based on the last 2 days. You can expect to find the cheapest price for the trip at R 684, which is on 2025-12-16.

          Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

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