Bus from Santander to Madrid: Tickets & Schedules

Next bus departures

Next departures for Santander to Madrid on December 2
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
ALSABus
    		Santander (Estacion de Autobuses)
    		Avenida de América MetroCheapest
    ALSA SupraBus
      		Santander (Estacion de Autobuses)
      		Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4Fastest
      ALSA SupraBus
        		Santander (Estacion de Autobuses)
        		Aeropuerto Adolfo Suárez Madrid-Barajas, MAD T4No tags
        FlixbusBus
        		Santander (Estacion de Autobuses)
        		Madrid (South)No tags
        ALSA SupraBus
          		Santander (Estacion de Autobuses)
          		Avenida de América MetroNo tags

          Last refresh of the prices: Today at 12:46 PM CET.

          Compare 3 ways to go from Santander to Madrid

          We recommend carpooling

          Among the sustainable travel choices, the carpool stands out as the good way to reach Madrid. The journey takes about 4 hours 20 minutes and with fares starting at just $20, it presents an excellent value for a comfortable ride.

          21carpool per day
          4h 20mAverage Duration
          211 milesDistance
          14kgCO₂ emissions
          Bus
          		Average Price$43 - $211Average Duration5h 40m
          8kg CO₂e
          Train
          		Average Price$33 - $99Average Duration4h 16m
          8kg CO₂e
          Carpool
          		Average Price$20 - $55Average Duration4h 20m
          14kg CO₂e

          Frequently asked questions about traveling from Santander to Madrid by bus

          Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

          1. How much is the bus ticket from Santander to Madrid?

            The cheapest bus tickets from Santander to Madrid start from $43. The average price for this route is around $54. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

          2. How long is the bus ride from Santander to Madrid?

            The average bus trip duration from Santander to Madrid is 5h 40m, covering a distance of 209 miles (337 km). The quickest bus can get you there in 5h and is operated by ALSA.

          3. Which bus companies service the Santander to Madrid route?

            Several major bus companies operate on this route with 14 buses available per day, including services from ALSA, FlixBus.

          4. What is the earliest and latest departure time for the bus from Santander to Madrid?

            The earliest bus departs from Santander to Madrid at 12:45am. And the latest bus departs at 6:55pm.

          5. What are the CO₂ emissions for the bus trip from Santander to Madrid?

            A bus trip from Santander to Madrid generates an estimated 8 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

          6. What is the best bus company from Santander to Madrid?

            According to Busbud customers, the highest-rated bus company on this route is ALSA, with an average rating of 4.3 out of 5 stars based on 60787 reviews.

          7. Which bus company has the best Wi-Fi from Santander to Madrid?

            Based on reviews on Busbud, the bus company ALSA has the best Wi-Fi rating with a score of 3.5.

          8. Which bus company has the most timely service from Santander to Madrid?

            According to Busbud traveller reviews, the most timely bus company on this route is ALSA, with a punctuality rating of 4.3 out of 5 stars.

          9. Which bus company has the cleanest buses from Santander to Madrid?

            According to Busbud traveller reviews, the bus company with the cleanest buses on this route is ALSA, with a cleanliness rating of 4.7 out of 5 stars.

          Find cheapest prices for buses

          Price is for a one-way ticket for one passenger and based on past searches.

          Best price found
          11/29
          $38
          11/30
          $97
          Today
          $38
          12/02
          $38
          12/03
          $38
          12/04
          $38
          12/05
          $38
          12/06
          $38
          busbud logoThe cheapest trip from Santander to Madrid was searched and found on Nov 29, 2025 with a price of $38

          To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santander to Madrid, as early as possible.

          You can expect to pay from $38 to $113 for a bus ticket from Santander to Madrid based on the last 2 days. You can expect to find the cheapest price for the trip at $38 which is on 2025-12-04.

          Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

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