How much is the bus ticket from Siena to Milano?

The cheapest bus tickets from Siena to Milano start at R 204. The average price for this route is around R 522. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.

How long is the bus journey from Siena to Milano?

The average bus journey time from Siena to Milano is 6h 35m, covering a distance of 329 km. The fastest bus gets you there in 4h 30m and is operated by FlixBus .

Which bus companies service the Siena to Milano route?

Several major bus companies operate on this route with 32 buses available per day, including services from FlixBus , Itabus .

What is the earliest and latest departure time for the bus from Siena to Milano?

The earliest bus departs from Siena to Milano at 00:45. And the latest bus departs at 23:55.

What are the CO₂ emissions for the bus trip from Siena to Milano?

A bus trip from Siena to Milano produces an estimated 8 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.

What is the best bus company from Siena to Milano?

According to Busbud customers, the highest-rated bus company on this route is Itabus , with an average rating of 3.8 out of 5 stars based on 968 reviews.

Which bus company has the best Wi-Fi from Siena to Milano?

Based on reviews on Busbud, the bus company Itabus has the best Wi-Fi rating with a score of 3.0.

Which bus company offers the most punctual service from Siena to Milano?

According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus , with a punctuality rating of 3.9 out of 5 stars.

Which bus company has the cleanest buses from Siena to Milano?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Itabus , with a cleanliness rating of 4.3 out of 5 stars.

Bus Siena to Milano from R 183 | Refundable Tickets

Next bus departures

Next departures from Siena to Milano on 4 January
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	19:45	Siena Train Station	5h 34m	01:19	Lampugnano bus station	Cheapest
Bus	00:45	Siena Train Station	4h 30m	05:15	Milan (San Donato M3)	Fastest
Bus	01:05	Siena Train Station	5h 50m	06:55	Lampugnano	No tags
Bus	00:45	Siena Train Station	9h 15m	10:00	Milan (Malpensa Aeroporto Terminal 1)	No tags
Bus	01:05	Siena Train Station	5h 50m	06:55	Lampugnano	No tags

Next departures from Siena to Milano on 6 January
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	21:55	Siena Train Station	6h 5m	04:00	Lampugnano bus station	Cheapest
Bus	00:45	Siena Train Station	4h 30m	05:15	Milan (San Donato M3)	Fastest
Bus	01:05	Siena Train Station	5h 50m	06:55	Lampugnano	No tags
Bus	00:45	Siena Train Station	9h 15m	10:00	Milan (Malpensa Aeroporto Terminal 1)	No tags
Bus	01:05	Siena Train Station	5h 50m	06:55	Lampugnano	No tags

Next departures from Siena to Milano on 7 January
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	18:35	Siena Train Station	6h	00:35	Lampugnano	Cheapest
Bus	00:45	Siena Train Station	4h 30m	05:15	Milan (San Donato M3)	Fastest
Bus	01:05	Siena Train Station	5h 50m	06:55	Lampugnano	No tags
Bus	00:45	Siena Train Station	9h 15m	10:00	Milan (Malpensa Aeroporto Terminal 1)	No tags
Bus	01:05	Siena Train Station	5h 50m	06:55	Lampugnano	No tags

Next departures from Siena to Milano on 8 January
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	01:05	Siena Train Station	5h 50m	06:55	Lampugnano	Cheapest
Bus	00:45	Siena Train Station	4h 30m	05:15	Milan (San Donato M3)	Fastest
Bus	01:05	Siena Train Station	5h 50m	06:55	Lampugnano	No tags
Bus	00:45	Siena Train Station	9h 15m	10:00	Milan (Malpensa Aeroporto Terminal 1)	No tags
Bus	01:05	Siena Train Station	5h 50m	06:55	Lampugnano	No tags

Next departures from Siena to Milano on 9 January
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	01:05	Siena Train Station	5h 50m	06:55	Lampugnano	Cheapest
Bus	00:45	Siena Train Station	4h 30m	05:15	Milan (San Donato M3)	Fastest
Bus	01:05	Siena Train Station	5h 50m	06:55	Lampugnano	No tags
Bus	00:45	Siena Train Station	9h 15m	10:00	Milan (Malpensa Aeroporto Terminal 1)	No tags
Bus	01:05	Siena Train Station	5h 50m	06:55	Lampugnano	No tags

Next departures from Siena to Milano on 10 January
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	01:05	Siena Train Station	5h 50m	06:55	Lampugnano	Cheapest
Bus	00:45	Siena Train Station	4h 30m	05:15	Milan (San Donato M3)	Fastest
Bus	01:05	Siena Train Station	5h 50m	06:55	Lampugnano	No tags
Bus	00:45	Siena Train Station	9h 15m	10:00	Milan (Malpensa Aeroporto Terminal 1)	No tags
Bus	01:05	Siena Train Station	5h 50m	06:55	Lampugnano	No tags

Last refresh of the prices: Today at 7:55 PM CET.

Compare 2 ways to travel from Siena to Milano

We recommend carpooling

Among the sustainable travel choices, the carpool stands out as a good way to reach Milano. The journey takes about 3 hours 40 minutes and with fares starting at just R 250, it presents an excellent value for a comfortable ride.

10carpool per day

3h 40mAverage duration

293 kmDistance

12kgCO₂ emissions

	Average price	Average duration	CO₂ emissions	Actions
Bus	Average priceR 204 - R 2 656	Average duration6h 35m	CO₂ emissions 8kg CO₂e
Carpool	Average priceR 250 - R 814	Average duration3h 40m	CO₂ emissions 12kg CO₂e

Where are the popular stops in Siena and Milano?

Stops in Siena

A
Piazza Gramsci
Piazza Antonio Gramsci, 53100 Siena SI, Italy
Visit page
B
Via Sallustio Bandini, 21
Via Sallustio Bandini, 21, 53100 Siena SI, Italy
C
Via Giuseppe Mazzini, 58
Via Giuseppe Mazzini, 58, 53100 Siena SI, Italy
D
Via Riccardo Lombardi, 42
Via Riccardo Lombardi, 42, 53100 Siena SI, Italy
E
Torre Fiorentina
Torre Fiorentina, 53100 Siena SI, Italy
F
Siena Zona Industriale
Siena FS, 53100 Siena SI, Italy

Stops in Milano

A
Lampugnano
Via Giulio Natta, 228, 20151 Milano, Italy
Visit page
B
Piazza I Maggio, 1
Piazza I Maggio, 1, 20099 Sesto San Giovanni MI, Italy
Visit page
C
Linate Airport
D
Malpensa Airport
Visit page
E
Milan San Donato Bus Station
Via Giuseppe Impastato, 27, 20138 Milano, Italy
Visit page
F
Molino Dorino
Molino Dorino, 20151 Milano, Italy

Compare bus companies

FlixBus

3.5/511 879 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

WiFi2.7

Itabus

4/5968 reviews

Staff4.3

Timeliness2.9

Cleanliness4.3

WiFi3.1

IT bus companies:FlixBus, BlaBlaCar Bus, Greyhound, ALSA, Intercape, Rede Expressos, Trenitalia

Frequently asked questions about travelling from Siena to Milano by bus

Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.

How much is the bus ticket from Siena to Milano?
The cheapest bus tickets from Siena to Milano start at R 204. The average price for this route is around R 522. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Siena to Milano?
The average bus journey time from Siena to Milano is 6h 35m, covering a distance of 329 km. The fastest bus gets you there in 4h 30m and is operated by FlixBus.
Which bus companies service the Siena to Milano route?
Several major bus companies operate on this route with 32 buses available per day, including services from FlixBus, Itabus.
What is the earliest and latest departure time for the bus from Siena to Milano?
The earliest bus departs from Siena to Milano at 00:45. And the latest bus departs at 23:55.
What are the CO₂ emissions for the bus trip from Siena to Milano?
A bus trip from Siena to Milano produces an estimated 8 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
What is the best bus company from Siena to Milano?
According to Busbud customers, the highest-rated bus company on this route is Itabus, with an average rating of 3.8 out of 5 stars based on 968 reviews.
Which bus company has the best Wi-Fi from Siena to Milano?
Based on reviews on Busbud, the bus company Itabus has the best Wi-Fi rating with a score of 3.0.
Which bus company offers the most punctual service from Siena to Milano?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Siena to Milano?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Itabus, with a cleanliness rating of 4.3 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

01/01

R 285

02/01

R 1 272

Today

R 462

04/01

R 417

05/01

R 426

06/01

R 691

07/01

R 183

08/01

R 183

The cheapest trip from Siena to Milano was searched and found on 07 Jan 2026 with a price of R 183

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Siena to Milano as early as possible.

You can expect to pay from R 183 to R 2 864 for a bus ticket from Siena to Milano based on the last 2 days. You can expect to find the cheapest price for the trip at R 183, which is on 2026-01-07.

Usually Itabus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.