Next bus departures

Next departures for Siena to Milano on October 21
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus Wifi Toilet Power outlets	10:55am	Siena Train Station	5h 45m	4:40pm	Lampugnano	CheapestFastest
Bus Wifi Toilet Power outlets	1:05am	Siena Train Station	5h 50m	6:55am	Lampugnano	No tags
Bus Wifi Toilet Power outlets	1:05am	Siena Train Station	5h 50m	6:55am	Lampugnano	No tags
Bus Wifi Toilet Power outlets	1:05am	Siena Train Station	5h 50m	6:55am	Lampugnano	No tags
Bus Wifi Toilet Power outlets	1:05am	Siena Train Station	5h 50m	6:55am	Lampugnano	No tags
Bus Wifi Toilet Power outlets	10:55am	Siena Train Station	5h 45m	4:40pm	Lampugnano	No tags
Bus Wifi Toilet Power outlets	10:55am	Siena Train Station	5h 45m	4:40pm	Lampugnano	No tags
Bus Wifi Toilet Power outlets	10:55am	Siena Train Station	5h 45m	4:40pm	Lampugnano	No tags

Last refresh of the prices: Yesterday at 9:58 PM CEST.

Get from Siena to Milano

This route is served by bus only

The journey takes about 6 hours 30 minutes and with fares starting at just $10, it presents an excellent value for a comfortable ride.

18bus per day

6h 30mAverage Duration

187 milesDistance

8kgCO₂ emissions

Bus stations and stops in Siena and Milano

Stops in Siena

A
Piazza Gramsci
Piazza Antonio Gramsci, 53100 Siena SI, Italy
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B
Via Sallustio Bandini, 21
Via Sallustio Bandini, 21, 53100 Siena SI, Italy
C
Via Giuseppe Mazzini, 58
Via Giuseppe Mazzini, 58, 53100 Siena SI, Italy
D
Via Riccardo Lombardi, 42
Via Riccardo Lombardi, 42, 53100 Siena SI, Italy
E
Torre Fiorentina
Torre Fiorentina, 53100 Siena SI, Italy
F
Siena Zona Industriale
Siena FS, 53100 Siena SI, Italy

Stops in Milano

A
Lampugnano
Via Giulio Natta, 228, 20151 Milano, Italy
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B
Piazza I Maggio, 1
Piazza I Maggio, 1, 20099 Sesto San Giovanni MI, Italy
Visit page
C
Linate Airport
Visit page
D
Malpensa Airport
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E
Milan San Donato Bus Station
Via Giuseppe Impastato, 27, 20138 Milano, Italy
Visit page
F
Molino Dorino
Molino Dorino, 20151 Milano, Italy

Compare bus companies

FlixBus

3.5/516,287 reviews

Staff4.2

Timeliness4.0

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

Itabus

3.8/51,092 reviews

Staff4.3

Timeliness3.1

Cleanliness4.1

Wifi2.8

IT bus companies:FlixBus, BlaBlaCar Bus, ALSA, Rede Expressos, Trenitalia, Deutsche Bahn, Sindbad

Frequently asked questions about traveling from Siena to Milano by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Siena to Milano?
The cheapest bus tickets from Siena to Milano start from $10. The average price for this route is around $26. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Siena to Milano?
The average bus trip duration from Siena to Milano is 6h 30m, covering a distance of 187 miles (301 km). The quickest bus can get you there in 4h 30m and is operated by FlixBus.
Which bus companies service the Siena to Milano route?
Several major bus companies operate on this route with 18 buses available per day, including services from FlixBus, Itabus.
What is the earliest and latest departure time for the bus from Siena to Milano?
The earliest bus departs from Siena to Milano at 12:45am. And the latest bus departs at 8:25pm.
What are the CO₂ emissions for the bus trip from Siena to Milano?
A bus trip from Siena to Milano generates an estimated 7.504824999999999 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Siena to Milano?
According to Busbud customers, the highest-rated bus company on this route is Itabus, with an average rating of 3.8 out of 5 stars based on 1090 reviews.
Which bus company has the best Wi-Fi from Siena to Milano?
Based on reviews on Busbud, the bus company Itabus has the best Wi-Fi rating with a score of 2.8.
Which bus company has the most timely service from Siena to Milano?
According to Busbud traveler reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Siena to Milano?
According to Busbud traveler reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

10/16

$35

10/17

$13

Today

$15

10/19

10/20

$17

10/21

$15

10/22

10/23

$10

The cheapest trip from Siena to Milano was searched and found on Oct 22, 2026 with a price of $8

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Siena to Milano, as early as possible.

You can expect to pay from $8 to $110 for a bus ticket from Siena to Milano based on the last 2 days. You can expect to find the cheapest price for the trip at $8 which is on 2026-10-22.