What is the travel distance from Siena to Milano?

The distance between Siena and Milano is around 294 km (182 miles).

What are the departure and arrival locations for buses traveling from Siena to Milano?

Buses traveling this route start their trip at Piazza Gramsci, in Siena, and end it at Lampugnano, in Milano.

Bus Siena to Milano from $16 | Refundable Tickets

Next bus departures

Next departures for Siena to Milano on November 21
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	7:45pm	Siena Train Station	5h 34m	1:19am	Lampugnano bus station	Cheapest
Bus	4:05pm	Siena Train Station	4h 50m	8:55pm	Milan (San Donato M3)	Fastest
Bus	6:35pm	Siena Train Station	6h	12:35am	Lampugnano	No tags
Bus	12:15pm	Siena Train Station	7h 50m	8:05pm	Milan (Malpensa Aeroporto Terminal 1)	No tags
Bus	6:35pm	Siena Train Station	6h	12:35am	Lampugnano	No tags

Next departures for Siena to Milano on November 23
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	6:10am	Siena Train Station	5h 45m	11:55am	Lampugnano bus station	Cheapest
Bus	12:45am	Siena Train Station	4h 30m	5:15am	Milan (San Donato M3)	Fastest
Bus	1:05am	Siena Train Station	5h 50m	6:55am	Lampugnano	No tags
Bus	12:45am	Siena Train Station	9h 15m	10:00am	Milan (Malpensa Aeroporto Terminal 1)	No tags
Bus	1:05am	Siena Train Station	5h 50m	6:55am	Lampugnano	No tags

Next departures for Siena to Milano on November 24
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	6:35pm	Siena Train Station	6h	12:35am	Lampugnano	Cheapest
Bus	12:45am	Siena Train Station	4h 30m	5:15am	Milan (San Donato M3)	Fastest
Bus	1:05am	Siena Train Station	5h 50m	6:55am	Lampugnano	No tags
Bus	12:45am	Siena Train Station	9h 15m	10:00am	Milan (Malpensa Aeroporto Terminal 1)	No tags
Bus	1:05am	Siena Train Station	5h 50m	6:55am	Lampugnano	No tags

Next departures for Siena to Milano on November 25
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	12:15pm	Siena Train Station	5h 40m	5:55pm	Lampugnano bus station	Cheapest
Bus	12:45am	Siena Train Station	4h 30m	5:15am	Milan (San Donato M3)	Fastest
Bus	1:05am	Siena Train Station	5h 50m	6:55am	Lampugnano	No tags
Bus	12:45am	Siena Train Station	9h 15m	10:00am	Milan (Malpensa Aeroporto Terminal 1)	No tags
Bus	1:05am	Siena Train Station	5h 50m	6:55am	Lampugnano	No tags

Next departures for Siena to Milano on November 26
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	12:15pm	Siena Train Station	5h 40m	5:55pm	Lampugnano bus station	Cheapest
Bus	12:45am	Siena Train Station	4h 30m	5:15am	Milan (San Donato M3)	Fastest
Bus	1:05am	Siena Train Station	5h 50m	6:55am	Lampugnano	No tags
Bus	12:45am	Siena Train Station	9h 15m	10:00am	Milan (Malpensa Aeroporto Terminal 1)	No tags
Bus	1:05am	Siena Train Station	5h 50m	6:55am	Lampugnano	No tags

Next departures for Siena to Milano on November 27
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	7:45pm	Siena Train Station	5h 34m	1:19am	Lampugnano bus station	Cheapest
Bus	12:45am	Siena Train Station	4h 30m	5:15am	Milan (San Donato M3)	Fastest
Bus	1:05am	Siena Train Station	5h 50m	6:55am	Lampugnano	No tags
Bus	12:45am	Siena Train Station	9h 15m	10:00am	Milan (Malpensa Aeroporto Terminal 1)	No tags
Bus	1:05am	Siena Train Station	5h 50m	6:55am	Lampugnano	No tags

Last refresh of the prices: Today at 10:32 AM CET.

Compare 2 ways to go from Siena to Milano

We recommend carpooling

Among the sustainable travel choices, the carpool stands out as a good way to reach Milano. The journey takes about 3 hours 40 minutes, and with fares starting at just $22, it presents an excellent value for a comfortable ride.

7carpool per day

3h 40mAverage Duration

293 kmDistance

12kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$18 - $241	Average Duration6h 30m	CO₂ emissions 7kg CO₂e
Carpool	Average Price$22 - $131	Average Duration3h 40m	CO₂ emissions 12kg CO₂e

Where are the popular stops in Siena and Milano?

Stops in Siena

A
Piazza Gramsci
Piazza Antonio Gramsci, 53100 Siena SI, Italy
Visit page
B
Via Sallustio Bandini, 21
Via Sallustio Bandini, 21, 53100 Siena SI, Italy
C
Via Giuseppe Mazzini, 58
Via Giuseppe Mazzini, 58, 53100 Siena SI, Italy
D
Via Riccardo Lombardi, 42
Via Riccardo Lombardi, 42, 53100 Siena SI, Italy
E
Torre Fiorentina
Torre Fiorentina, 53100 Siena SI, Italy
F
Siena Zona Industriale
Siena FS, 53100 Siena SI, Italy

Stops in Milano

A
Lampugnano
Via Giulio Natta, 228, 20151 Milano, Italy
Visit page
B
Piazza I Maggio, 1
Piazza I Maggio, 1, 20099 Sesto San Giovanni MI, Italy
Visit page
C
Linate Airport
Visit page
D
Malpensa Airport
Visit page
E
Milan San Donato Bus Station
Via Giuseppe Impastato, 27, 20138 Milano, Italy
Visit page
F
Molino Dorino
Molino Dorino, 20151 Milano, Italy

Compare bus companies

FlixBus

3.5/511,388 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

Wifi2.7

Itabus

4/5946 reviews

Staff4.3

Timeliness3

Cleanliness4.3

Wifi3.1

IT Bus Companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Rede Expressos, Trenitalia

Frequently asked questions about travelling from Siena to Milano by bus

What is the travel distance from Siena to Milano?
The distance between Siena and Milano is around 294 km (182 miles).
What are the departure and arrival locations for buses traveling from Siena to Milano?
Buses traveling this route start their trip at Piazza Gramsci, in Siena, and end it at Lampugnano, in Milano.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11-19

$31

11-20

$26

Today

$30

11-22

$26

11-23

$36

11-24

$16

11-25

$18

11-26

$23

The cheapest trip from Siena to Milano was searched and found on Nov 24, 2025 with a price of $16

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Siena to Milano, as early as possible.

You can expect to pay from $16 to $156 for a bus ticket from Siena to Milano based on the last 2 days. You can expect to find the cheapest price for the trip at $16 which is on 2025-11-24.

Usually Itabus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.