- Spartanburg to Indianapolis buses
Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound + FlixBus | Bus | Spartanburg | Downtown Transit Center | No tags | ||||
FlixBus + Greyhound | Bus | Spartanburg | Downtown Transit Center | No tags | ||||
![]() | Bus | Spartanburg | Downtown Transit Center | No tags | ||||
FlixBus + Greyhound | Bus | Spartanburg | Indianapolis Bus Station | No tags | ||||
Greyhound + FlixBus | Bus | Spartanburg | Indianapolis Bus Station | No tags |
Compare 2 ways to go from Spartanburg to Indianapolis
We recommend taking the bus
Among the sustainable travel choices, the bus stands out as a good way to reach Indianapolis. The journey takes about 16 hours 10 minutes, and with fares starting at just $171, it presents an excellent value for a comfortable ride.
5bus per day
16h 10mAverage Duration
645 kmDistance
16kgCO₂ emissions
Where are the popular stops in Spartanburg and Indianapolis?
Stops in Spartanburg
- A9133 Fairforest Rd. Spartanburg, SC , C.P. 29301
- B
Spartanburg Bus Stop
1402 E Main St, Spartanburg, SC 29307, USA - C
Sparta Passenger Center
100 Liberty St, Spartanburg, SC 29306, USA
Compare bus companies
US Bus Companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad
Frequently asked questions about travelling from Spartanburg to Indianapolis by bus
What is the travel distance from Spartanburg to Indianapolis?
The distance between Spartanburg and Indianapolis is around 654 km (406 miles).
What are the departure and arrival locations for buses traveling from Spartanburg to Indianapolis?
Buses traveling this route start their trip at Super Acapulco, in Spartanburg, and end it at Greyhound Amtrak Station, in Indianapolis.







