Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Gateway Station | Syracuse (Regional Transportation Center) | Cheapest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Gateway Station | Syracuse (Regional Transportation Center) | Fastest |
Last refresh of the prices: Yesterday at 9:37 AM CST.
Compare 2 ways to travel from St. Louis to Syracuse
Among the sustainable travel choices, the Train stands out as a good way to reach Syracuse. The journey takes about 19 hours 33 minutes and with fares starting at just R 2 631, it presents an excellent value for a comfortable ride.
Where are the popular stops in St. Louis and Syracuse?
Stops in Syracuse
- A
Regional Transportation Center
1 Walsh Circle Ste 30, Syracuse, NY 13208 - B
Syracuse Airport
- CBus stops at Schine Student Center across the street from the Sheraton Parking Garage., Schine Student Center, 303 University Pl, Syracuse, NY 13210
- D
Syracuse University - Lyman Hall
College Place, Syracuse, NY 13210, USA - E
New York State Fairgrounds
581 State Fair Blvd, Syracuse, NY 13209, USA - F
Syracuse, NY
349-399 US-11, Syracuse, NY 13202, USA
Compare bus companies
Based on 87500 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. Greyhound ticket prices on this trip start at R 1 927
Frequently asked questions about travelling from St. Louis to Syracuse, US by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from St. Louis to Syracuse?
The cheapest bus tickets from St. Louis to Syracuse start at R 1 911. The average price for this route is around R 2 592. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from St. Louis to Syracuse?
The average bus journey time from St. Louis to Syracuse is 1d 5h, covering a distance of 1278 km. The fastest bus gets you there in 1d 5h and is operated by Greyhound.
Which bus companies service the St. Louis to Syracuse route?
Several major bus companies operate on this route with 1 buses available per day.
What is the earliest and latest departure time for the bus from St. Louis to Syracuse?
The earliest bus departs from St. Louis to Syracuse at 08:45. And the latest bus departs at 13:45.
What are the CO₂ emissions for the bus trip from St. Louis to Syracuse?
A bus trip from St. Louis to Syracuse produces an estimated 32 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from St. Louis to Syracuse, US was searched and found on 18 Jan 2026 with a price of R 1 807To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from St. Louis to Syracuse, US as early as possible.
You can expect to pay from R 1 807 to R 3 227 for a bus ticket from St. Louis to Syracuse, US based on the last 2 days. You can expect to find the cheapest price for the trip at R 1 807, which is on 2026-01-18.
What's the cheapest way to go from St. Louis to Syracuse, US?
The Bus is the cheapest travel choice for this destination
