Previously seen journeys
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Terminal Interbus | Rome Fiumicino Airport | No tags | |||||
| Terminal Interbus | Aeroporto Ciampino Airport (CIA) | No tags | |||||
| Terminal Interbus | Rome Fiumicino Airport | No tags | |||||
| Terminal Interbus | Rome Tiburtina Bus Station | No tags | |||||
| Terminal Interbus | Rome Anagnina | No tags |
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Compare 3 ways to travel from Syracuse to Rome
Among the sustainable travel choices, the bus stands out as a good way to reach Rome. The journey takes about 19 hours 50 minutes and with fares starting at just US$41, it presents an excellent value for a comfortable ride.
Bus Syracuse to Rome: Trip Overview
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Syracuse to Rome Bus
With Busbud, comparing and booking tickets for a bus from Syracuse to Rome is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
We make it our job to connect you with the most dependable bus companies that cover bus service from Syracuse to Rome.
Whether it is cheap bus tickets or more luxurious buses going to Rome from Syracuse, we help you find what you're looking for based on how much of a budget you have.
Where are the popular stops in Syracuse and Rome?
Frequently asked questions on the trip Syracuse - Rome
How much does a bus ticket from Syracuse to Rome cost?
The bus ticket price from Syracuse to Rome starts at US$41. The best way to find cheap bus tickets from Syracuse to Rome is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the bus ride from Syracuse to Rome?
The average travel time between Syracuse and Rome is around 19h 50m, although the fastest bus will take about 14h. This is the time it takes to travel the 588 km that separates the two cities.
How many daily bus connections are there between Syracuse and Rome?
The number of buses from Syracuse to Rome can differ depending on the day of the week. On average, there are 4 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Syracuse to Rome by comparing and selecting the bus that fits your travel style and budget on Busbud.
Which bus companies travel from Syracuse to Rome?
When taking the bus from Syracuse to Rome, you can travel comfortably and safely with FlixBus, FlixBus.
What are the departure and arrival stations when taking the bus from Syracuse to Rome?
Buses travelling between Syracuse and Rome leave from Fermata dell'autobus Siracusa or Siracusa and arrive at Rome Tiburtina Bus Station, Rome Ciampino Airport, Rome Fiumicino Airport.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Syracuse to Rome was searched and found on 31 Oct 2025 with a price of US$44To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Syracuse to Rome as early as possible.
You can expect to pay from US$44 to US$161 for a bus ticket from Syracuse to Rome based on the last 2 days. You can expect to find the cheapest price for the trip at US$57, which is on 2025-11-01.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while travelling from Syracuse to Rome.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Syracuse to Rome.
Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Syracuse to Rome.
Tune out to the fine sounds of your best music playlist on your bus trip from Syracuse to Rome while indulging in miles on end of beautiful scenic views.
Did you know?
The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.
Top travelled bus routes
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Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.
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Popular Buses Connecting Syracuse
Buses Leaving from Syracuse
- Bus from Syracuse to Florence
- Coach Syracuse - Taormina
- Bus Syracuse - Catania
- Bus from Syracuse to Paris
- Coach Syracuse - Palermo
- Bus Syracuse - Noto
- Bus from Syracuse to Giardini Naxos
- Coach Syracuse - Cassibile
- Bus Syracuse - San Giovanni Rotondo
- Bus from Syracuse to Lecce
- Coach Syracuse - Letojanni
- Bus Syracuse - Naples
- Bus from Syracuse to Prato
- Coach Syracuse - Avezzano
- Bus Syracuse - Pachino
Buses Going to Syracuse
- Bus from Noto to Syracuse
- Coach Palermo - Syracuse
- Bus Paris - Syracuse
- Bus from Taormina to Syracuse
- Coach Pachino - Syracuse
- Bus Giardini Naxos - Syracuse
- Bus from Florence to Syracuse
- Coach Naples - Syracuse
- Bus Rosolini - Syracuse
- Bus from Cesena to Syracuse
- Coach Lanciano - Syracuse
- Bus Senigallia - Syracuse
- Bus from Mantua to Syracuse
- Coach Trento - Syracuse
- Bus Gioia Tauro - Syracuse
Popular Buses Connecting Rome
Buses Leaving from Rome
- Bus from Rome to Como
- Coach Rome - Fiumicino
- Bus Rome - Naples
- Bus from Rome to Tours
- Coach Rome - Outlet
- Bus Rome - Amalfi
- Bus from Rome to Monselice
- Coach Rome - San Severo
- Bus Rome - Oulx
- Bus from Rome to Caltanissetta
- Coach Rome - Verona
- Bus Rome - Spezzano Scalo
- Bus from Rome to Sparvasile
- Coach Rome - Misano Adriatico
- Bus Rome - Grottaminarda
Buses Going to Rome
- Bus from Milano to Rome
- Coach Venice - Rome
- Bus Civitavecchia - Rome
- Bus from Rimini to Rome
- Coach Barcelona - Rome
- Bus Nice - Rome
- Bus from Gallipoli to Rome
- Coach Terlizzi - Rome
- Bus Benevento - Rome
- Bus from Barletta to Rome
- Coach Pozzallo - Rome
- Bus Ostuni - Rome
- Bus from Bitonto to Rome
- Coach Marsico Nuovo - Rome
- Bus Amalfi - Rome