Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Price and booking link |
|---|---|---|---|---|---|---|---|
 | Bus
| Terminal Interbus | Aeroporto Ciampino Airport (CIA) | ||||
| Bus
| Terminal Interbus | Rome Tiburtina Bus Station | ||||
| Bus
| Terminal Interbus | Rome Fiumicino Airport | ||||
| Bus
| Terminal Interbus | Rome Tiburtina Bus Station | ||||
| Bus
| Terminal Interbus | Rome Anagnina |
Compare 2 ways to go from Syracuse to Rome
Among the sustainable travel choices, the Train stands out as a good way to reach Rome. The journey takes about 10 hours 51 minutes, and with fares starting at just MAD 918, it presents an excellent value for a comfortable ride.
Bus stations and stops in Syracuse and Rome
Stops in Syracuse
- A
Fermata dell'autobus Siracusa
Viale Paolo Orsi, 20, 96100 Siracusa SR, Italy - B
Siracusa
Piazzale della Stazione Centrale, 21, 96100 Siracusa SR, Italy - C
Siracusa - Terminal Bus (Stazione FS)
Viale Teocrito, 68-74, 96100 Siracusa SR, Italy
Stops in Rome
- B
Rome Tiburtina Bus Station
Largo Guido Mazzoni, 3, 00162 Roma, Italy - D
Castro Pretorio
Viale Castro Pretorio 76, 00185 Roma, Italy - E
Roma
- F
Anagnina
Via Vincenzo Giudice, 00173 Roma RM, Italy
Compare bus companies
Based on 16023 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi‑Fi. FlixBus ticket prices on this trip start at MAD 409
Frequently asked questions about travelling from Syracuse to Rome by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Syracuse to Rome?
The cheapest bus tickets from Syracuse to Rome start from MAD 409. The average price for this route is around MAD 755. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Syracuse to Rome?
The average bus travel time from Syracuse to Rome is 14h 35m, covering a distance of 583 km. The quickest bus can get you there in 13h 30m and is operated by FlixBus.
Which bus companies service the Syracuse to Rome route?
Several major bus companies operate on this route with 5 buses available per day.
What are the earliest and latest departure times for the bus from Syracuse to Rome?
The earliest bus departs from Syracuse to Rome at 7:15am. And the latest bus departs at 5:20pm.
What are the CO₂ emissions for the bus trip from Syracuse to Rome?
A bus trip from Syracuse to Rome generates an estimated 14.56925 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Syracuse to Rome was searched and found on Oct 6, 2026 with a price of MAD 387To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Syracuse to Rome, as early as possible.
You can expect to pay from MAD 387 to MAD 1,456 for a bus ticket from Syracuse to Rome based on the last 2 days. You can expect to find the cheapest price for the trip at MAD 387 which is on 2026-10-06.
