Find coaches from Wilmington, DE to Winston-Salem

Next departures

Next departures from Wilmington to Winston-Salem on 31 October
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus + Greyhound Lines, Inc.
Newark (DE)
Winston Salem Greyhound Bus StationCheapestFastest
Greyhound Lines, Inc.
Wilmington Bus Station
Winston Salem Greyhound Bus StationNo tags
Greyhound Lines, Inc. + FlixBus
Wilmington Bus Station
Winston Salem Greyhound Bus StationNo tags
FlixBus + Greyhound Lines, Inc.
Newark (DE)
Winston Salem Greyhound Bus StationNo tags
FlixBus + Greyhound Lines, Inc.
Delaware Rest Stop S
Winston Salem Greyhound Bus StationNo tags

Last refresh of the prices: Today at 4:18 AM EDT.

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Get from Wilmington to Winston-Salem

busbud logoThis route is served by bus only

The journey takes about 16 hours 55 minutes, and with fares starting at just US$90, it presents an excellent value for a comfortable ride.

6bus per day
16h 55mAverage duration
578 kmDistance
14kgCO₂ emissions

Bus Wilmington, DE to Winston-Salem: Trip Overview

Average ticket priceUS$101
Average bus trip duration16h 55m
Number of daily buses6
Earliest bus departure02:50
Distance577 km
Latest bus departure21:25

Wilmington to Winston-Salem Bus

Busbud helps you find a bus from Wilmington to Winston-Salem. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make it our job to connect you with the most dependable bus companies that cover bus service from Wilmington to Winston-Salem.

From cheap bus tickets to more luxurious buses travelling from Wilmington to Winston-Salem, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Wilmington, DE - Winston-Salem

  1. How much does a bus ticket from Wilmington to Winston-Salem cost?

    The bus ticket price from Wilmington to Winston-Salem starts at US$90. The best way to find cheap bus tickets from Wilmington to Winston-Salem is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

  2. How long is the bus ride from Wilmington to Winston-Salem?

    The average travel time between Wilmington and Winston-Salem is around 16h 55m, although the fastest bus will take about 11h 15m. This is the time it takes to travel the 577 km that separates the two cities.

  3. How many daily bus connections are there between Wilmington and Winston-Salem?

    The number of buses from Wilmington to Winston-Salem can differ depending on the day of the week. On average, there are 6 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Wilmington to Winston-Salem by comparing and selecting the bus that fits your travel style and budget on Busbud.

  4. Which bus companies travel from Wilmington to Winston-Salem?

    When taking the bus from Wilmington to Winston-Salem, you can travel comfortably and safely with Greyhound.

  5. What are the departure and arrival stations when taking the bus from Wilmington to Winston-Salem?

    Buses travelling between Wilmington and Winston-Salem leave from Wilmington Bus Station or Wilmington Station and arrive at Winston Salem Greyhound Bus Station, E Sprague St, Winston-Salem Bus Stop.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
28/10
US$91
29/10
No data
Today
No data
31/10
US$82
01/11
No data
02/11
No data
03/11
No data
04/11
No data
busbud logoThe cheapest trip from Wilmington, DE to Winston-Salem was searched and found on 31 Oct 2025 with a price of US$82

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Wilmington, DE to Winston-Salem as early as possible.

You can expect to pay from US$82 to US$91 for a bus ticket from Wilmington, DE to Winston-Salem based on the last 2 days. You can expect to find the cheapest price for the trip at US$82, which is on 2025-10-31.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Wilmington and Winston-Salem!

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Wilmington to Winston-Salem.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Wilmington to Winston-Salem that are otherwise impossible to come by with a plane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Wilmington to Winston-Salem.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Will you be returning to Wilmington, DE by bus?

Bus from Winston-Salem to Wilmington, DE

Why choose Busbud?

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