Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Bus | Delaware Rest Stop S | Winston Salem Greyhound Bus Station | Cheapest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Newark (DE) | Winston Salem Greyhound Bus Station | Fastest | ||||
 | Bus | Wilmington Bus Station | Winston Salem Greyhound Bus Station | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Newark (DE) | Winston Salem Greyhound Bus Station | No tags | ||||
| Bus | Wilmington Bus Station | Winston Salem Greyhound Bus Station | No tags |
Last refresh of the prices: Last Monday at 10:25 AM EST.
Get from Wilmington to Winston-Salem
The journey takes about 17 hours 20 minutes, and with fares starting at just R 1 227, it presents an excellent value for a comfortable ride.
Where are the popular stops in Wilmington and Winston-Salem?
Stops in Wilmington
- AWilmington Bus Station, 101 N French St, Wilmington, DE 19801, USA
- B100 French St, Wilmington, DE 19801, USA
- C
Wilmington Bus Stop
101 N French , Wilmington, DE 19801
Stops in Winston-Salem
- A
Winston Salem Greyhound Bus Station
100 W 5th St, Winston Salem, NC 27101 - B
E Sprague St
841 E Sprague St, Winston-Salem, NC 27107, USA - C
Winston-Salem Bus Stop
2500 Old Lexington Rd, Winston-Salem, NC 27107, USA - D
1237 Silas Creek Pkwy
1237 Silas Creek Pkwy., Winston-Salem, NC 27127 (Hong Kong King Buffet)
Compare bus companies
Based on 87521 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained about the Wi-Fi. Greyhound ticket prices on this trip start at R 1 227
Frequently asked questions about travelling from Wilmington, DE to Winston-Salem by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Wilmington to Winston-Salem?
The cheapest bus tickets from Wilmington to Winston-Salem start at R 1 227. The average price for this route is around R 1 902. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Wilmington to Winston-Salem?
The average bus journey time from Wilmington to Winston-Salem is 17h 20m, covering a distance of 563 km. The fastest bus gets you there in 16h 55m and is operated by Greyhound.
Which bus companies service the Wilmington to Winston-Salem route?
Several major bus companies operate on this route with 6 buses available per day.
What is the earliest and latest departure time for the bus from Wilmington to Winston-Salem?
The earliest bus departs from Wilmington to Winston-Salem at 02:50. And the latest bus departs at 21:25.
What are the CO₂ emissions for the bus trip from Wilmington to Winston-Salem?
A bus trip from Wilmington to Winston-Salem produces an estimated 14 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Wilmington, DE to Winston-Salem was searched and found on 09 Feb 2026 with a price of R 1 258To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Wilmington, DE to Winston-Salem as early as possible.
You can expect to pay from R 1 258 to R 2 385 for a bus ticket from Wilmington, DE to Winston-Salem based on the last 2 days. You can expect to find the cheapest price for the trip at R 1 258, which is on 2026-02-09.
