How can I travel from Wilmington to Winston-Salem without flying?

You have the option of traveling from one city to the other by either bus or train. The two options are easy and eco-friendly ways to reach Winston-Salem. Another option you should consider is using carpooling services, which allow you to share a car ride with other travelers.

How long does it take to get to Winston-Salem from Wilmington by bus?

The travel time from Wilmington to Winston-Salem is about 16h 15m, but the fastest bus can get you there in about 13h 25m. This is the time it takes to travel the 358 miles (577 km) that separate the two cities.

What is the travel distance from Wilmington to Winston-Salem?

About 358 miles (577 km) separate Wilmington and Winston-Salem.

What are the departure and arrival stations when taking the bus from Wilmington to Winston-Salem?

The majority of buses traveling from Wilmington to Winston-Salem start their journey at Wilmington Bus Station and wind up at Winston Salem Greyhound Bus Station. These are the main departure and arrival locations on this route, but you could find others that could be a better fit for your travel plans.

What is the most cost-effective way to travel from Wilmington to Winston-Salem?

Go for the bus if you want the most cost-effective way to travel this route. The lowest price for the bus on this route is $122.

How much are the bus tickets from Wilmington to Winston-Salem?

The average price of a one-way ticket from Wilmington to Winston-Salem is $142. In the past 30 days, prices have fluctuated between $122 and $142, so it's best to compare them to make sure you get the best deal.

Is there an overnight bus from Wilmington to Winston-Salem?

Yes, you can take a night bus to go from Wilmington to Winston-Salem. Remember to bring along essentials like a blanket and some snacks to ensure a cozy and convenient journey.

Wilmington (DE) to Winston-Salem Bus Tickets

Compare 2 ways to go from Wilmington to Winston-Salem.

	Average Price	Average Duration	CO₂ emissions
Bus	Average Price$122 - $142	Average Duration16h 15m	CO₂ emissions 14kg CO₂e5 out of 5 stars	CheapestMost eco-friendly
Train	Average Price$225 - $225	Average Duration11h 15m	CO₂ emissions 52kg CO₂e1 out of 5 stars	Fastest

Busbud recommends taking the train from Wilmington to Winston-Salem

Among the sustainable travel choices, the train stands out as the good way to reach Winston-Salem. The journey takes about 11 hours 15 minutes and with fares starting at just $225, it presents an excellent value for a comfortable ride.

2train per day

11h 15mAverage Duration

$225Cheapest ticket

52kgCO₂ emissions

Bus Wilmington to Winston-Salem: Trip Overview

Average ticket price$142

Average bus trip duration16h 15m

Number of daily buses3

Earliest bus departure1:45am

Distance358 miles (577 km)

Latest bus departure9:25pm

Compare bus companies

Greyhound

3.5/586,986 reviews

Staff3.6

Timeliness2.8

Cleanliness3.3

Wifi2.3

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

US bus companies: FlixBus, Greyhound, Los Limousines, Tornado Bus, Valley Transit, Tufesa, Wanda Coach

Wilmington to Winston-Salem Bus

Busbud helps you find a bus from Wilmington to Winston-Salem. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make it our job to connect you with the most dependable bus companies that cover bus service from Wilmington to Winston-Salem.

From cheap bus tickets to more luxurious buses traveling from Wilmington to Winston-Salem, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Where are the popular stops in Wilmington and Winston-Salem?

Stops in Wilmington

A - Wilmington Bus Station

B - Wilmington Station

C - Wilmington Bus Stop

Stops in Winston-Salem

A - Winston Salem Greyhound Bus Station

B - E Sprague St

C - Winston-Salem Bus Stop

D - 1237 Silas Creek Pkwy

Frequently asked questions for your trip Wilmington - Winston-Salem

How can I travel from Wilmington to Winston-Salem without flying?
How long does it take to get to Winston-Salem from Wilmington by bus?
What is the travel distance from Wilmington to Winston-Salem?
What are the departure and arrival stations when taking the bus from Wilmington to Winston-Salem?
What is the most cost-effective way to travel from Wilmington to Winston-Salem?
How much are the bus tickets from Wilmington to Winston-Salem?
Is there an overnight bus from Wilmington to Winston-Salem?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

05/16

No data

05/17

$93

Today

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05/20

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The cheapest trip from Wilmington to Winston-Salem was searched and found on May 17, 2025 with a price of $93

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Wilmington to Winston-Salem, as early as possible.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Wilmington and Winston-Salem!

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Wilmington to Winston-Salem.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Wilmington to Winston-Salem that are otherwise impossible to come by with a plane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Wilmington to Winston-Salem.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

What's the cheapest way to go from Wilmington to Winston-Salem?

The bus is the cheapest travel choice for this destination

Vehicle Type	Travel Time	Avg Price	Daily Departures
Vehicle TypeBus	Travel Time16h 15m	Avg Price$142	Daily Departures3
Vehicle TypeTrain	Travel Time11h 15m	Avg Price$225	Daily Departures2

Will you be returning to Wilmington by bus?

Bus from Wilmington to Winston-Salem

You can also go to Winston-Salem by train

Train from Wilmington to Winston-Salem

Top traveled bus routes

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travelers find a bus, plot routes, and book intercity bus tickets all over the world. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

Bus Tickets from Wilmington, DE to Winston-Salem, NC

Compare 2 ways to go from Wilmington to Winston-Salem.

Bus Wilmington to Winston-Salem: Trip Overview

Compare bus companies

Wilmington to Winston-Salem Bus

Where are the popular stops in Wilmington and Winston-Salem?

Frequently asked questions for your trip Wilmington - Winston-Salem

How can I travel from Wilmington to Winston-Salem without flying?

How long does it take to get to Winston-Salem from Wilmington by bus?

What is the travel distance from Wilmington to Winston-Salem?

What are the departure and arrival stations when taking the bus from Wilmington to Winston-Salem?

What is the most cost-effective way to travel from Wilmington to Winston-Salem?

How much are the bus tickets from Wilmington to Winston-Salem?

Is there an overnight bus from Wilmington to Winston-Salem?

Find cheapest prices for buses

About Bus Travel

Bus Travel Tips

Did you know?

What's the cheapest way to go from Wilmington to Winston-Salem?

Will you be returning to Wilmington by bus?

You can also go to Winston-Salem by train

Top traveled bus routes

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

People from around the world trust Busbud

Popular Buses Connecting Wilmington

Buses Leaving from Wilmington

Buses Going to Wilmington

Popular Buses Connecting Winston-Salem

Buses Leaving from Winston-Salem

Buses Going to Winston-Salem

Popular routes in this country

Popular airport transfers