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- This trip is recommended because it is: Cheapest + FastestDeparture time: July 6 atDeparture city: WilmingtonDeparture location: Wilmington Bus StationArrival time: July 7 atDestination city: Winston-SalemDestination location: Winston Salem Greyhound Bus StationOperated by: Greyhound Lines, Inc.
Vehicle: BusDuration: - Departure time: July 6 atDeparture city: WilmingtonDeparture location: Wilmington Bus StationArrival time: July 6 atDestination city: Winston-SalemDestination location: Winston Salem Greyhound Bus StationOperated by: Greyhound Lines, Inc.Vehicle: BusDuration:
- Departure time: July 6 atDeparture city: WilmingtonDeparture location: Wilmington Bus StationArrival time: July 7 atDestination city: Winston-SalemDestination location: Winston Salem Greyhound Bus StationOperated by: Greyhound Lines, Inc.Vehicle: BusDuration:
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Compare 2 ways to go from Wilmington to Winston-Salem.
Busbud recommends taking the bus from Wilmington to Winston-SalemAmong the sustainable travel choices, the bus stands out as the good way to reach Winston-Salem. The journey takes about 16 hours 15 minutes and with fares starting at just $109, it presents an excellent value for a comfortable ride.
Bus Wilmington to Winston-Salem: Trip Overview
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Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Wilmington to Winston-Salem Bus
Busbud helps you find a bus from Wilmington to Winston-Salem. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
We make it our job to connect you with the most dependable bus companies that cover bus service from Wilmington to Winston-Salem.
From cheap bus tickets to more luxurious buses traveling from Wilmington to Winston-Salem, we offer a wide range of bus services to best suit your needs depending on how much your budget is.
Where are the popular stops in Wilmington and Winston-Salem?
Frequently asked questions for your trip Wilmington, DE - Winston-Salem
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Wilmington to Winston-Salem was searched and found on Jul 6, 2025 with a price of $102To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Wilmington to Winston-Salem, as early as possible.
You can expect to pay from $102 to $132 for a bus ticket from Wilmington to Winston-Salem based on the last 2 days. You can expect to find the cheapest price for the trip at $102 which is on 2025-07-06.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Wilmington and Winston-Salem!
From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Wilmington to Winston-Salem.
Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Wilmington to Winston-Salem that are otherwise impossible to come by with a plane.
Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Wilmington to Winston-Salem.
Did you know?
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.
The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.
What's the cheapest way to go from Wilmington to Winston-Salem?
The bus is the cheapest travel choice for this destinationTop traveled bus routes
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